8JIP
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![BU of 8jip by Molmil](/molmil-images/mine/8jip) | Cryo-EM structure of the GLP-1R/GCGR dual agonist MEDI0382-bound human GLP-1R-Gs complex | Descriptor: | Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Yang, L, Zhou, Q.T, Dai, A.T, Zhao, F.H, Chang, R.L, Ying, T.L, Wu, B.L, Yang, D.H, Wang, M.W, Cong, Z.T. | Deposit date: | 2023-05-27 | Release date: | 2023-09-06 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Structural analysis of the dual agonism at GLP-1R and GCGR. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JIR
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![BU of 8jir by Molmil](/molmil-images/mine/8jir) | Cryo-EM structure of the GLP-1R/GCGR dual agonist SAR425899-bound human GLP-1R-Gs complex | Descriptor: | Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Yang, L, Zhou, Q.T, Dai, A.T, Zhao, F.H, Chang, R.L, Ying, T.L, Wu, B.L, Yang, D.H, Wang, M.W, Cong, Z.T. | Deposit date: | 2023-05-27 | Release date: | 2023-09-06 | Method: | ELECTRON MICROSCOPY (2.57 Å) | Cite: | Structural analysis of the dual agonism at GLP-1R and GCGR. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JIT
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![BU of 8jit by Molmil](/molmil-images/mine/8jit) | Cryo-EM structure of the GLP-1R/GCGR dual agonist MEDI0382-bound human GCGR-Gs complex | Descriptor: | Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Yang, L, Zhou, Q.T, Dai, A.T, Zhao, F.H, Chang, R.L, Ying, T.L, Wu, B.L, Yang, D.H, Wang, M.W, Cong, Z.T. | Deposit date: | 2023-05-27 | Release date: | 2023-09-06 | Method: | ELECTRON MICROSCOPY (2.91 Å) | Cite: | Structural analysis of the dual agonism at GLP-1R and GCGR. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JIQ
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![BU of 8jiq by Molmil](/molmil-images/mine/8jiq) | Cryo-EM structure of the GLP-1R/GCGR dual agonist Peptide 15-bound human GCGR-Gs complex | Descriptor: | Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Yang, L, Zhou, Q.T, Dai, A.T, Zhao, F.H, Chang, R.L, Ying, T.L, Wu, B.L, Yang, D.H, Wang, M.W, Cong, Z.T. | Deposit date: | 2023-05-27 | Release date: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural analysis of the dual agonism at GLP-1R and GCGR. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JIU
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![BU of 8jiu by Molmil](/molmil-images/mine/8jiu) | Cryo-EM structure of the GLP-1R/GCGR dual agonist SAR425899-bound human GCGR-Gs complex | Descriptor: | Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Yang, L, Zhou, Q.T, Dai, A.T, Zhao, F.H, Chang, R.L, Ying, T.L, Wu, B.L, Yang, D.H, Wang, M.W, Cong, Z.T. | Deposit date: | 2023-05-27 | Release date: | 2023-09-13 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | Structural analysis of the dual agonism at GLP-1R and GCGR. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JIS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8jis by Molmil](/molmil-images/mine/8jis) | Cryo-EM structure of the GLP-1R/GCGR dual agonist peptide15-bound human GLP-1R-Gs complex | Descriptor: | Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Yang, L, Zhou, Q.T, Dai, A.T, Zhao, F.H, Chang, R.L, Ying, T.L, Wu, B.L, Yang, D.H, Wang, M.W, Cong, Z.T. | Deposit date: | 2023-05-27 | Release date: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (2.46 Å) | Cite: | Structural analysis of the dual agonism at GLP-1R and GCGR. Proc.Natl.Acad.Sci.USA, 120, 2023
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