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PDB: 1 results

6T41
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BU of 6t41 by Molmil
CDK8/Cyclin C in complex with N-(4-chlorobenzyl)isoquinolin-4-amine
Descriptor: 1,2-ETHANEDIOL, Cyclin-C, Cyclin-dependent kinase 8, ...
Authors:Schneider, E.V, Maskos, K, Huber, R, Kuhn, C.-D.
Deposit date:2019-10-11
Release date:2020-01-01
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:A precisely positioned MED12 activation helix stimulates CDK8 kinase activity.
Proc.Natl.Acad.Sci.USA, 117, 2020

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