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PDB: 2 results

3AMA
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BU of 3ama by Molmil
Protein kinase A sixfold mutant model of Aurora B with inhibitor JNJ-7706621
Descriptor: 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1H-1,2,4-triazol-3-yl}amino)benzenesulfonamide, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha
Authors:Pflug, A, de Oliveira, T.M, Bossemeyer, D, Engh, R.A.
Deposit date:2010-08-18
Release date:2011-08-03
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Mutants of protein kinase A that mimic the ATP-binding site of Aurora kinase
Biochem.J., 440, 2011
3AMB
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BU of 3amb by Molmil
Protein kinase A sixfold mutant model of Aurora B with inhibitor VX-680
Descriptor: CYCLOPROPANECARBOXYLIC ACID {4-[4-(4-METHYL-PIPERAZIN-1-YL)-6-(5-METHYL-2H-PYRAZOL-3-YLAMINO)-PYRIMIDIN-2-YLSULFANYL]-PHENYL}-AMIDE, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha
Authors:Pflug, A, de Oliveira, T.M, Bossemeyer, D, Engh, R.A.
Deposit date:2010-08-18
Release date:2011-08-03
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Mutants of protein kinase A that mimic the ATP-binding site of Aurora kinase
Biochem.J., 440, 2011

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