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Mouse fumarylacetoacetate hydrolase complexes with a transition-state mimic of the complete substrate
Descriptor:	4-(2-CARBOXYETHYL)(HYDROXY)PHOSPHORYL]-3-OXOBUTANOIC ACID, CALCIUM ION, Fumarylacetoacetase, ...
Authors:	Hurley, T.D, Timm, D.E.
Deposit date:	2006-08-09
Release date:	2006-08-22
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (1.35 Å)
Cite:	Slow-onset inhibition of fumarylacetoacetate hydrolase by phosphinate mimics of the tetrahedral intermediate: kinetics, crystal structure and pharmacokinetics. Biochem.J., 402, 2007