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8BK3
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Crystal structure of the transpeptidase LdtMt2 from Mycobacterium tuberculosis in complex with diepoxide ketone 1
Descriptor: 1,2-ETHANEDIOL, 1-[(2~{S},3~{R})-3-phenyloxiran-2-yl]ethanone, DIMETHYL SULFOXIDE, ...
Authors:de Munnik, M, Schofield, C.J.
Deposit date:2022-11-08
Release date:2023-11-22
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:alpha beta , alpha ' beta '-Diepoxyketones are mechanism-based inhibitors of nucleophilic cysteine enzymes.
Chem.Commun.(Camb.), 59, 2023

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