PDB Search results for query - Protein Data Bank Japan

PDB: 2 results

One active site, two modes of reduction correlate the mechanism of leishmania pteridine reductase with pterin metabolism and antifolate drug resistance in trpanosomes
Descriptor:	1,2-ETHANEDIOL, METHOTREXATE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:	Gourley, D.G, Hunter, W.N.
Deposit date:	2000-09-11
Release date:	2001-09-06
Last modified:	2011-07-13
Method:	X-RAY DIFFRACTION (1.75 Å)
Cite:	Pteridine Reductase Mechanism Correlates Pterin Metabolism with Drug Resistance in Trypanosomatid Parasites. Nat.Struct.Biol., 8, 2001

Pteridine reductase 1 from Leishmania major complexed with NADP+ and dihydrobiopterin
Descriptor:	1,2-ETHANEDIOL, 7,8-DIHYDROBIOPTERIN, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:	Schuettelkopf, A.W, Hunter, W.N.
Deposit date:	2000-10-04
Release date:	2001-10-05
Last modified:	2023-12-13
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Pteridine Reductase Mechanism Correlates Pterin Metabolism with Drug Resistance in Trypanosomatid Parasites Nat.Struct.Biol., 8, 2001