9KQV
 
 | | Cryo-EM structure of MPXV core protease in complex with aloxistatin(E64d) | | Descriptor: | Core protease I7, ethyl (3S)-3-hydroxy-4-({(2S)-4-methyl-1-[(3-methylbutyl)amino]-1-oxopentan-2-yl}amino)-4-oxobutanoate | | Authors: | Lan, W, You, T, Li, D, Dong, X, Wang, H, Xu, J, Wang, W, Gao, Y, Yang, H. | | Deposit date: | 2024-11-27 | | Release date: | 2025-03-12 | | Last modified: | 2025-07-16 | | Method: | ELECTRON MICROSCOPY (2.93 Å) | | Cite: | Substrate recognition and cleavage mechanism of the monkeypox virus core protease.
Nature, 643, 2025
|
|
9KR6
 | | Cryo-EM structure of MPXV core protease in complex with the substrate derivative I-G18 | | Descriptor: | Core protease I7, Core protein VP8 | | Authors: | Lan, W, You, T, Li, D, Dong, X, Wang, H, Xu, J, Wang, W, Gao, Y, Yang, H. | | Deposit date: | 2024-11-27 | | Release date: | 2025-03-12 | | Last modified: | 2025-07-16 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Substrate recognition and cleavage mechanism of the monkeypox virus core protease.
Nature, 643, 2025
|
|
9JAL
 | | Cryo-EM structure of MPXV core protease in complex with compound A1 | | Descriptor: | A1ECM-DI8-ALA-ETA, Core protease I7 | | Authors: | Gao, Y, Xie, X, Lan, W, Wang, W, Yang, H. | | Deposit date: | 2024-08-25 | | Release date: | 2025-03-12 | | Last modified: | 2025-07-16 | | Method: | ELECTRON MICROSCOPY (3.03 Å) | | Cite: | Substrate recognition and cleavage mechanism of the monkeypox virus core protease.
Nature, 643, 2025
|
|
9JAM
 | | Cryo-EM structure of MPXV core protease in complex with compound A3 | | Descriptor: | A1ECK-DI8-ALA-AEM, Core protease I7 | | Authors: | Gao, Y, Xie, X, Lan, W, Wang, W, Yang, H. | | Deposit date: | 2024-08-25 | | Release date: | 2025-03-12 | | Last modified: | 2025-07-16 | | Method: | ELECTRON MICROSCOPY (2.98 Å) | | Cite: | Substrate recognition and cleavage mechanism of the monkeypox virus core protease.
Nature, 643, 2025
|
|
9JAQ
 | | Cryo-EM structure of MPXV core protease in the apo-form | | Descriptor: | Core protease I7 | | Authors: | Lan, W, You, T, Li, D, Dong, X, Wang, H, Xu, J, Wang, W, Gao, Y, Yang, H. | | Deposit date: | 2024-08-25 | | Release date: | 2025-03-12 | | Last modified: | 2025-07-16 | | Method: | ELECTRON MICROSCOPY (2.99 Å) | | Cite: | Substrate recognition and cleavage mechanism of the monkeypox virus core protease.
Nature, 643, 2025
|
|
9JAN
 | | Cryo-EM structure of MPXV protease in complex with compound A4 | | Descriptor: | A1ECL-DI8-ALA-AEM, Core protease I7 | | Authors: | Gao, Y, Xie, X, Lan, W, Wang, W, Yang, H. | | Deposit date: | 2024-08-25 | | Release date: | 2025-03-12 | | Last modified: | 2025-07-16 | | Method: | ELECTRON MICROSCOPY (2.93 Å) | | Cite: | Substrate recognition and cleavage mechanism of the monkeypox virus core protease.
Nature, 643, 2025
|
|
