9DTG
 
 | | The cryo-EM structure of apo KBTBD4 | | Descriptor: | Isoform 2 of Kelch repeat and BTB domain-containing protein 4 | | Authors: | Xie, X, Mao, H, Liau, B, Zheng, N. | | Deposit date: | 2024-09-30 | | Release date: | 2024-11-27 | | Last modified: | 2025-03-19 | | Method: | ELECTRON MICROSCOPY (3.83 Å) | | Cite: | UM171 glues asymmetric CRL3-HDAC1/2 assembly to degrade CoREST corepressors.
Nature, 639, 2025
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8VOJ
 | | The Cryo-EM structure of LSD1-CoREST-HDAC1 in complex with KBTBD4 enhanced by UM171 and IP6 | | Descriptor: | (1r,4r)-N~1~-[(7P)-2-benzyl-7-(2-methyl-2H-tetrazol-5-yl)-9H-pyrimido[4,5-b]indol-4-yl]cyclohexane-1,4-diamine, Histone deacetylase 1, INOSITOL HEXAKISPHOSPHATE, ... | | Authors: | Xie, X, Mao, H, Liau, B, Zheng, N. | | Deposit date: | 2024-01-15 | | Release date: | 2024-12-04 | | Last modified: | 2025-06-18 | | Method: | ELECTRON MICROSCOPY (3.77 Å) | | Cite: | UM171 glues asymmetric CRL3-HDAC1/2 assembly to degrade CoREST corepressors.
Nature, 639, 2025
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