PDB Search results for query - Protein Data Bank Japan

PDB: 3 results

Structure of VACV Poxin in post-reactive state with Gp[2'-5']Ap[3']
Descriptor:	2',5'-GpAp, Protein B2
Authors:	Eaglesham, J.B, Kranzusch, P.J.
Deposit date:	2018-08-02
Release date:	2019-02-06
Last modified:	2024-03-13
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Viral and metazoan poxins are cGAMP-specific nucleases that restrict cGAS-STING signalling. Nature, 566, 2019

Structure of VACV poxin in pre-reactive state with nonhydrolyzable 2'3' cGAMP
Descriptor:	(2S,5R,7R,8R,10R,12aR,14R,15R,15aS,16R)-7-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-14-(6-amino-9H-purin-9-yl)-15,16-dihydroxy-2,10-disulfanyloctahydro-2H,10H,12H-5,8-methano-2lambda~5~,10lambda~5~-furo[3,2-l][1,3,6,9,11,2,10]pentaoxadiphosphacyclotetradecine-2,10-dione, O-[(1R,2R,3R)-5-{[(S)-{[(2R,3R,4R,5R)-2-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)tetrahydro furan-3-yl]oxy}(sulfanyl)phosphoryl]oxy}-1-(6-amino-9H-purin-9-yl)-1,2-dihydroxypentan-3-yl] dihydrogen (R)-phosphorothioate, Protein B2
Authors:	Eaglesham, J.B, Kranzusch, P.J.
Deposit date:	2018-08-02
Release date:	2019-02-06
Last modified:	2024-03-13
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Viral and metazoan poxins are cGAMP-specific nucleases that restrict cGAS-STING signalling. Nature, 566, 2019

Structure of VACV poxin 2'3' cGAMP-specific nuclease
Descriptor:	Protein B2
Authors:	Eaglesham, J.B, Kranzusch, P.J.
Deposit date:	2018-08-02
Release date:	2019-02-06
Last modified:	2019-12-11
Method:	X-RAY DIFFRACTION (1.703 Å)
Cite:	Viral and metazoan poxins are cGAMP-specific nucleases that restrict cGAS-STING signalling. Nature, 566, 2019