8GMG
 
 | | CryoEM structure of P-Glycoprotein in Apo state | | Descriptor: | ATP-dependent translocase ABCB1 | | Authors: | Culbertson, A, Liao, M. | | Deposit date: | 2023-03-25 | | Release date: | 2025-04-23 | | Last modified: | 2025-05-21 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Cryo-EM of human P-glycoprotein reveals an intermediate occluded conformation during active drug transport.
Nat Commun, 16, 2025
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8GMJ
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8SBA
 | | CryoEM structure of P-Glycoprotein in inward facing 2 state under continuous turnover conditions with vinblastine | | Descriptor: | (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent translocase ABCB1, ... | | Authors: | Culbertson, A, Liao, M. | | Deposit date: | 2023-04-02 | | Release date: | 2025-04-23 | | Last modified: | 2025-06-04 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Cryo-EM of human P-glycoprotein reveals an intermediate occluded conformation during active drug transport.
Nat Commun, 16, 2025
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8SB8
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8SB9
 | | CryoEM structure of P-Glycoprotein in inward facing 1 state under continuous turnover conditions with vinblastine | | Descriptor: | (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent translocase ABCB1, ... | | Authors: | Culbertson, A, Liao, M. | | Deposit date: | 2023-04-02 | | Release date: | 2025-04-23 | | Last modified: | 2025-05-14 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Cryo-EM of human P-glycoprotein reveals an intermediate occluded conformation during active drug transport.
Nat Commun, 16, 2025
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8SA1
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8SA0
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8SB7
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