8WGB
 
 | | mGlu2-4 heterodimer bound with Gi | | Descriptor: | (1R,2S)-2-[[3,5-bis(chloranyl)phenyl]carbamoyl]cyclohexane-1-carboxylic acid, GLUTAMIC ACID, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Zhang, Y, Liu, J. | | Deposit date: | 2023-09-20 | | Release date: | 2024-10-30 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural basis of orientated asymmetry in a mGlu heterodimer.
Nat Commun, 15, 2024
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8WG9
 | | mGlu2-mGlu4 heterodimer bound mGlu4 agonist E7P | | Descriptor: | (2S)-2-amino-4-phosphonobutanoic acid, Metabotropic glutamate receptor 2, Metabotropic glutamate receptor 4 | | Authors: | Zhang, Y, Liu, J. | | Deposit date: | 2023-09-20 | | Release date: | 2024-11-27 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (4.46 Å) | | Cite: | Structural basis of orientated asymmetry in a mGlu heterodimer.
Nat Commun, 15, 2024
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8WGD
 | | mGlu2-4 inactive heterodimer | | Descriptor: | (1S,2R)-2-[(2S)-2-azanyl-1-oxidanyl-1-oxidanylidene-3-(9H-xanthen-9-yl)propan-2-yl]cyclopropane-1-carboxylic acid, (2S)-2-azanyl-2-cyclopropyl-2-(4-phosphonophenyl)ethanoic acid, Metabotropic glutamate receptor 2, ... | | Authors: | Zhang, Y, Liu, J. | | Deposit date: | 2023-09-20 | | Release date: | 2024-11-27 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (4.45 Å) | | Cite: | Structural basis of orientated asymmetry in a mGlu heterodimer.
Nat Commun, 15, 2024
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8WGC
 | | heterodimer of mGlu2 and mGlu4 bound with mGlu2 agonist LY379268 | | Descriptor: | (1R,4R,5S,6R)-4-azanyl-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid, Metabotropic glutamate receptor 2, Metabotropic glutamate receptor 4 | | Authors: | Zhang, Y, Liu, J. | | Deposit date: | 2023-09-20 | | Release date: | 2024-11-27 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (5.95 Å) | | Cite: | Structural basis of orientated asymmetry in a mGlu heterodimer.
Nat Commun, 15, 2024
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