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Complex of human thrombin (S195A) bound to a bivalent inhibitor comprised of DNA Aptamer HD22 conjugated to Dabigatran with a linker.
Descriptor:	2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, DNA (30-MER), ...
Authors:	Krishnaswamy, S, Kumar, S.
Deposit date:	2023-08-08
Release date:	2024-05-01
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (2.207 Å)
Cite:	Aptameric hirudins as selective and reversible EXosite-ACTive site (EXACT) inhibitors. Nat Commun, 15, 2024