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PDB: 5 results

7SHT
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BU of 7sht by Molmil
Structure of a partially disrupted IgE high affinity receptor complex bound to an omalizumab variant
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, High affinity immunoglobulin epsilon receptor subunit alpha, ...
Authors:Pennington, L.F, Jardetzky, T.S.
Deposit date:2021-10-11
Release date:2021-12-15
Method:ELECTRON MICROSCOPY (7.29 Å)
Cite:Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex.
Nat Commun, 12, 2021
7SI0
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BU of 7si0 by Molmil
IgE-Fc in complex with 813
Descriptor: 813 Variable fragment Heavy chain, 813 Variable fragment Light chain, IgE Fc, ...
Authors:Pennington, L.F, Jardetzky, T.J, Kleinboelting, S.
Deposit date:2021-10-12
Release date:2021-12-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex.
Nat Commun, 12, 2021
7SHY
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BU of 7shy by Molmil
IgE-Fc in complex with omalizumab scFv
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, IgE Fc, ...
Authors:Pennington, L.F, Jardetzky, T.J, Kleinboelting, S.
Deposit date:2021-10-11
Release date:2021-12-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex.
Nat Commun, 12, 2021
7SHU
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BU of 7shu by Molmil
IgE-Fc in complex with omalizumab variant C02
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin heavy constant epsilon, ...
Authors:Pennington, L.F, Jardetzky, T.J, Kleinboelting, S.
Deposit date:2021-10-11
Release date:2021-12-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex.
Nat Commun, 12, 2021
7SHZ
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BU of 7shz by Molmil
IgE-Fc in complex with HAE
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
Authors:Pennington, L.F, Jardetzky, T.J, Kleinboelting, S.
Deposit date:2021-10-11
Release date:2021-12-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex.
Nat Commun, 12, 2021

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