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PDB: 1 results

7D5C
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BU of 7d5c by Molmil
IleRS in complex with a tRNA site inhibitor
Descriptor: (2E,4S,5S,6E,8E)-10-[(2S,3R,6S,8R,9S)-3-butyl-9-methyl-2-[(1E,3E)-3-methyl-5-oxidanyl-5-oxidanylidene-penta-1,3-dienyl]-3-(4-oxidanyl-4-oxidanylidene-butanoyl)oxy-1,7-dioxaspiro[5.5]undecan-8-yl]-4,8-dimethyl-5-oxidanyl-deca-2,6,8-trienoic acid, 1,2-ETHANEDIOL, Isoleucine--tRNA ligase, ...
Authors:Chen, B, Luo, S, Zhou, H.
Deposit date:2020-09-25
Release date:2021-02-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.895 Å)
Cite:Inhibitory mechanism of reveromycin A at the tRNA binding site of a class I synthetase.
Nat Commun, 12, 2021

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