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Crystal structure of EGFR tyrosine kinase domain with novel inhibitor of active state of HER2
Descriptor:	3-(furan-2-yl)-N-[5-(furan-2-yl)-2-methoxyphenyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Epidermal growth factor receptor, SULFATE ION
Authors:	Park, J.H, Lemmon, M.A.
Deposit date:	2016-04-18
Release date:	2016-09-07
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (3.298 Å)
Cite:	Overcoming resistance to HER2 inhibitors through state-specific kinase binding. Nat.Chem.Biol., 12, 2016