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PDB: 2 results

4DUM
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BU of 4dum by Molmil
Co-crystal structure of eIF4E with inhibitor
Descriptor: (4-{7-[2-(4-chlorophenoxy)ethyl]-2-(methylamino)-6-oxo-6,7-dihydro-1H-purin-8-yl}phenyl)phosphonic acid, 1,2-ETHANEDIOL, Eukaryotic translation initiation factor 4E
Authors:Min, X, Johnstone, S, Walker, N, Wang, Z.
Deposit date:2012-02-22
Release date:2012-04-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structure-Guided Design, Synthesis, and Evaluation of Guanine-Derived Inhibitors of the eIF4E mRNA-Cap Interaction.
J.Med.Chem., 55, 2012
4DT6
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BU of 4dt6 by Molmil
Co-crystal structure of eIF4E with inhibitor
Descriptor: 1,2-ETHANEDIOL, 7-[2-(4-chlorophenoxy)ethyl]guanosine 5'-(dihydrogen phosphate), Eukaryotic translation initiation factor 4E, ...
Authors:Min, X, Johnstone, S, Walker, N, Wang, Z.
Deposit date:2012-02-20
Release date:2012-04-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure-Guided Design, Synthesis, and Evaluation of Guanine-Derived Inhibitors of the eIF4E mRNA-Cap Interaction.
J.Med.Chem., 55, 2012

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