PDB Search results for query - Protein Data Bank Japan

PDB: 2 results

Identification of M4205 a highly selective inhibitor of cKIT mutations for unresectable metastatic or recurrent GIST
Descriptor:	Mast/stem cell growth factor receptor Kit, ~{N}-[[4-(1-methylpyrazol-4-yl)phenyl]methyl]-6-[7-(3-pyrrolidin-1-ylpropoxy)imidazo[1,2-a]pyridin-3-yl]pyrimidin-4-amine
Authors:	Graedler, U, Lammens, A.
Deposit date:	2022-05-19
Release date:	2023-02-22
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (2.119 Å)
Cite:	Identification of M4205─A Highly Selective Inhibitor of KIT Mutations for Treatment of Unresectable Metastatic or Recurrent Gastrointestinal Stromal Tumors. J.Med.Chem., 66, 2023

Identification of M4205 a highly selective inhibitor of cKIT mutations for unresectable metastatic or recurrent GIST
Descriptor:	5-imidazo[1,2-a]pyridin-3-yl-~{N}-[(1~{R})-1-(6-pyrrolidin-1-ylpyridin-3-yl)ethyl]pyridin-3-amine, HUMAN PROTO-ONCOGENE C-KIT
Authors:	Graedler, U, Lammens, A.
Deposit date:	2022-05-24
Release date:	2023-02-22
Last modified:	2024-02-07
Method:	X-RAY DIFFRACTION (3.09 Å)
Cite:	Identification of M4205─A Highly Selective Inhibitor of KIT Mutations for Treatment of Unresectable Metastatic or Recurrent Gastrointestinal Stromal Tumors. J.Med.Chem., 66, 2023