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PDB: 1 results

6E3Z
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BU of 6e3z by Molmil
Structure of Bace-1 in complex with Ligand 8
Descriptor: Beta-secretase 1, N-{3-[(2R,3R)-5-amino-3-methyl-2-(trifluoromethyl)-3,6-dihydro-2H-1,4-oxazin-3-yl]-4-fluorophenyl}-3,5-dichloropyridine-2-carboxamide
Authors:Shaffer, P.L.
Deposit date:2018-07-16
Release date:2019-09-11
Last modified:2020-03-25
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Discovery and Chemical Development of JNJ-50138803, a Clinical Candidate BACE1 Inhibitor
Acs Symp.Ser., 1307, 2020

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