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PDB: 1 results

1CI7
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TERNARY COMPLEX OF THYMIDYLATE SYNTHASE FROM PNEUMOCYSTIS CARINII
Descriptor: 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, PROTEIN (THYMIDYLATE SYNTHASE)
Authors:Anderson, A.C, O'Neil, R.H, Delano, W.L, Stroud, R.M.
Deposit date:1999-04-08
Release date:2000-04-10
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The structural mechanism for half-the-sites reactivity in an enzyme, thymidylate synthase, involves a relay of changes between subunits.
Biochemistry, 38, 1999

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