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6SJM
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Crystal structure of the Retinoic Acid Receptor alpha in complex with compound 24 (JP175)
Descriptor: 2-[4-[3,5-bis(trifluoromethyl)phenyl]phenyl]ethanoic acid, Nuclear receptor coactivator 2, Retinoic acid receptor RXR-alpha
Authors:Chaikuad, A, Pollinger, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Merk, D, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2019-08-13
Release date:2019-09-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:A Novel Biphenyl-based Chemotype of Retinoid X Receptor Ligands Enables Subtype and Heterodimer Preferences.
Acs Med.Chem.Lett., 10, 2019

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