8XKP
 
 | | Crystal structure of human tyrosine-protein kinase Fes/Fps in complex with compound 17c | | Descriptor: | 7-[[(1R,2S)-2-azanylcyclohexyl]amino]-5-[[3-[(2S,6R)-2,6-dimethylmorpholin-4-yl]phenyl]amino]-4-oxidanylidene-3H-pyrido[3,4-d]pyridazine-8-carbonitrile, SULFATE ION, Tyrosine-protein kinase Fes/Fps | | Authors: | Baba, D, Hanzawa, H. | | Deposit date: | 2023-12-23 | | Release date: | 2025-01-01 | | Last modified: | 2025-03-19 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Optimization of Novel Pyrido-pyridazinone Derivatives as FER Tyrosine Kinase Inhibitors, Leading to the Potent DS08701581.
Acs Med.Chem.Lett., 15, 2024
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