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PDB: 4 results

8ZU2
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BU of 8zu2 by Molmil
Crystal Structure of Human Myt1 Kinase domain Bounded with compound 8g
Descriptor: 2-azanyl-5-[2-(1,4-diazepan-1-yl)pyridin-4-yl]-3-(2,6-dimethyl-3-oxidanyl-phenyl)benzamide, GLYCINE, Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
Authors:Zhang, Z.M, Zhou, Z.Q.
Deposit date:2024-06-07
Release date:2024-09-11
Last modified:2024-09-25
Method:X-RAY DIFFRACTION (1.79888582 Å)
Cite:Structure-Based Drug Design of 2-Amino-[1,1'-biphenyl]-3-carboxamide Derivatives as Selective PKMYT1 Inhibitors for the Treatment of CCNE1 -Amplified Breast Cancer.
J.Med.Chem., 67, 2024
8ZTX
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BU of 8ztx by Molmil
Crystal Structure of Human Myt1 Kinase domain Bounded with compound 6b
Descriptor: 2-azanyl-3-(2,6-dimethyl-3-oxidanyl-phenyl)-5-pyridin-4-yl-benzamide, Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
Authors:Zhang, Z.M, Zhou, Z.Q.
Deposit date:2024-06-07
Release date:2024-09-11
Last modified:2024-09-25
Method:X-RAY DIFFRACTION (1.70033228 Å)
Cite:Structure-Based Drug Design of 2-Amino-[1,1'-biphenyl]-3-carboxamide Derivatives as Selective PKMYT1 Inhibitors for the Treatment of CCNE1 -Amplified Breast Cancer.
J.Med.Chem., 67, 2024
8ZUD
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BU of 8zud by Molmil
Crystal Structure of Human Myt1 Kinase domain Bounded with compound 8f
Descriptor: 2-azanyl-3-(2,6-dimethyl-3-oxidanyl-phenyl)-5-(2-morpholin-4-ylpyridin-4-yl)benzamide, Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
Authors:Zhang, Z.M, Zhou, Z.Q.
Deposit date:2024-06-08
Release date:2024-09-11
Last modified:2024-09-25
Method:X-RAY DIFFRACTION (1.50510085 Å)
Cite:Structure-Based Drug Design of 2-Amino-[1,1'-biphenyl]-3-carboxamide Derivatives as Selective PKMYT1 Inhibitors for the Treatment of CCNE1 -Amplified Breast Cancer.
J.Med.Chem., 67, 2024
8ZUL
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BU of 8zul by Molmil
Crystal Structure of Human Myt1 Kinase domain Bounded with compound 8m
Descriptor: 2-azanyl-5-[2-[(3~{R})-3-azanylpyrrolidin-1-yl]pyridin-4-yl]-3-(2,6-dimethyl-3-oxidanyl-phenyl)benzamide, Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
Authors:Zhang, Z.M, Zhou, Z.Q.
Deposit date:2024-06-09
Release date:2024-09-11
Last modified:2024-09-25
Method:X-RAY DIFFRACTION (1.80026162 Å)
Cite:Structure-Based Drug Design of 2-Amino-[1,1'-biphenyl]-3-carboxamide Derivatives as Selective PKMYT1 Inhibitors for the Treatment of CCNE1 -Amplified Breast Cancer.
J.Med.Chem., 67, 2024

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PDB entries from 2024-12-18

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