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PDB: 2 results

Crystal structure of E. coli ClpP protease in complex with phosphine oxide compound ACP6-12
Descriptor:	2-{bis[5-(trifluoromethyl)pyridin-2-yl]phosphoryl}-2-methyl-N-(2-{[2-(trifluoromethyl)phenyl]sulfanyl}ethyl)propanamide, ATP-dependent Clp protease proteolytic subunit
Authors:	Mabanglo, M.F, Houry, W.A.
Deposit date:	2023-05-30
Release date:	2024-09-18
Last modified:	2024-09-25
Method:	X-RAY DIFFRACTION (2.35 Å)
Cite:	Structure-Based Design and Development of Phosphine Oxides as a Novel Chemotype for Antibiotics that Dysregulate Bacterial ClpP Proteases. J.Med.Chem., 67, 2024

Crystal structure of Neisseria meningitidis ClpP protease in complex with phosphine oxide compound ACP6-12
Descriptor:	2-{bis[5-(trifluoromethyl)pyridin-2-yl]phosphoryl}-2-methyl-N-(2-{[2-(trifluoromethyl)phenyl]sulfanyl}ethyl)propanamide, ATP-dependent Clp protease proteolytic subunit
Authors:	Mabanglo, M.F, Houry, W.A.
Deposit date:	2023-05-30
Release date:	2024-09-18
Last modified:	2024-09-25
Method:	X-RAY DIFFRACTION (2.33 Å)
Cite:	Structure-Based Design and Development of Phosphine Oxides as a Novel Chemotype for Antibiotics that Dysregulate Bacterial ClpP Proteases. J.Med.Chem., 67, 2024