PDB Search results for query - Protein Data Bank Japan

PDB: 2 results

The crystal structure of EGFR T790M/C797S with the inhibitor HCD2892
Descriptor:	5-chloranyl-N-[5-chloranyl-2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-4-(1-ethylsulfonylindol-3-yl)pyrimidin-2-amine, Epidermal growth factor receptor
Authors:	Zhu, S.J.
Deposit date:	2021-10-22
Release date:	2022-06-08
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (2.507 Å)
Cite:	Conformational Constrained 4-(1-Sulfonyl-3-indol)yl-2-phenylaminopyrimidine Derivatives as New Fourth-Generation Epidermal Growth Factor Receptor Inhibitors Targeting T790M/C797S Mutations. J.Med.Chem., 65, 2022

The crystal structure of EGFR T790M/C797S with the inhibitor HC5476
Descriptor:	25-chloro-11-(ethylsulfonyl)-44-morpholino-11H-5,12-dioxa-3-aza-1(3,6)-indola-2(4,2)-pyrimidina-4(1,3)-benzenacyclododecaphane, Epidermal growth factor receptor
Authors:	Zhu, S.J.
Deposit date:	2021-10-22
Release date:	2022-06-08
Last modified:	2023-11-29
Method:	X-RAY DIFFRACTION (2.41 Å)
Cite:	Conformational Constrained 4-(1-Sulfonyl-3-indol)yl-2-phenylaminopyrimidine Derivatives as New Fourth-Generation Epidermal Growth Factor Receptor Inhibitors Targeting T790M/C797S Mutations. J.Med.Chem., 65, 2022