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7WNX
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Cryo-EM structure of Mycobacterium smegmatis MmpL3 complexed with ST004 in lipid nanodiscs
Descriptor: N-[2-(2-adamantylamino)ethyl]-1-[2,4-bis(fluoranyl)phenyl]-5-(4-chlorophenyl)-4-methyl-pyrazole-3-carboxamide, Trehalose monomycolate exporter MmpL3
Authors:Zhang, B, Hu, T, Yang, X, Liu, F, Rao, Z.
Deposit date:2022-01-20
Release date:2022-08-03
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Structure-based design of anti-mycobacterial drug leads that target the mycolic acid transporter MmpL3.
Structure, 30, 2022

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