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Structure of the extracellular domain of human epidermal growth factor (EGF) receptor in an inactive (low pH) complex with EGF.
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:	Ferguson, K.M, Lemmon, M.A.
Deposit date:	2003-01-21
Release date:	2003-03-11
Last modified:	2023-08-16
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	EGF activates its receptor by removing interactions that auto-inhibit ectodomain dimerization Mol.Cell, 11, 2003