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PDB: 2 results

5AVI
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BU of 5avi by Molmil
Crystal structure of LXRalpha in complex with tert-butyl benzoate analog, compound 4
Descriptor: Nuclear receptor coactivator 1, Oxysterols receptor LXR-alpha, tert-butyl 2-[[4-[ethanoyl(methyl)amino]phenoxy]methyl]-5-(trifluoromethyl)benzoate
Authors:Matsui, Y, Hanzawa, H, Tamaki, K.
Deposit date:2015-06-16
Release date:2015-08-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Discovery and structure-guided optimization of tert-butyl 6-(phenoxymethyl)-3-(trifluoromethyl)benzoates as liver X receptor agonists
Bioorg.Med.Chem.Lett., 25, 2015
5AVL
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BU of 5avl by Molmil
Crystal structure of LXRalpha in complex with tert-butyl benzoate analog, compound 32b
Descriptor: 2-[4-[4-[[2-[(2-methylpropan-2-yl)oxycarbonyl]-3-oxidanyl-4-(trifluoromethyl)phenyl]methoxy]phenyl]phenyl]ethanoic acid, Nuclear receptor coactivator 1, Oxysterols receptor LXR-alpha
Authors:Matsui, Y, Hanzawa, H, Tamaki, K.
Deposit date:2015-06-17
Release date:2015-08-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Discovery and structure-guided optimization of tert-butyl 6-(phenoxymethyl)-3-(trifluoromethyl)benzoates as liver X receptor agonists
Bioorg.Med.Chem.Lett., 25, 2015

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