8SFI
 
 | | WT CRISPR-Cas12a with a 8bp R-loop | | Descriptor: | CRISPR-associated endonuclease Cas12a, DNA (5'-D(P*CP*TP*TP*AP*TP*CP*AP*CP*TP*AP*AP*AP*AP*GP*AP*TP*CP*GP*GP*AP*AP*G)-3'), DNA (5'-D(P*CP*TP*TP*CP*CP*GP*AP*TP*CP*TP*TP*TP*TP*AP*GP*TP*GP*AP*TP*A)-3'), ... | | Authors: | Strohkendl, I, Taylor, D.W. | | Deposit date: | 2023-04-11 | | Release date: | 2024-07-03 | | Last modified: | 2025-01-22 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Cas12a domain flexibility guides R-loop formation and forces RuvC resetting.
Mol.Cell, 84, 2024
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8SFN
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8SFR
 | | WT CRISPR-Cas12a post nontarget strand cleavage. | | Descriptor: | CRISPR-associated endonuclease Cas12a, DNA (34-MER), DNA (5'-D(P*CP*TP*TP*CP*CP*GP*AP*TP*CP*TP*TP*TP*TP*AP*GP*TP*GP*AP*T)-3'), ... | | Authors: | Strohkendl, I, Taylor, D.W. | | Deposit date: | 2023-04-11 | | Release date: | 2024-07-03 | | Last modified: | 2025-01-22 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Cas12a domain flexibility guides R-loop formation and forces RuvC resetting.
Mol.Cell, 84, 2024
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8SFQ
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8SFO
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8SFJ
 | | WT CRISPR-Cas12a with a 10bp R-loop | | Descriptor: | CRISPR-associated endonuclease Cas12a, DNA (5'-D(P*CP*AP*CP*TP*TP*AP*TP*CP*AP*CP*TP*AP*AP*AP*AP*GP*AP*TP*CP*GP*GP*AP*AP*G)-3'), DNA (5'-D(P*CP*TP*TP*CP*CP*GP*AP*TP*CP*TP*TP*TP*TP*AP*GP*TP*GP*AP*T)-3'), ... | | Authors: | Strohkendl, I, Taylor, D.W. | | Deposit date: | 2023-04-11 | | Release date: | 2024-07-03 | | Last modified: | 2025-01-22 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Cas12a domain flexibility guides R-loop formation and forces RuvC resetting.
Mol.Cell, 84, 2024
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8SFH
 | | WT CRISPR-Cas12a with a 5bp R-loop | | Descriptor: | CRISPR-associated endonuclease Cas12a, DNA (32-MER), RNA (27-MER) | | Authors: | Strohkendl, I, Taylor, D.W. | | Deposit date: | 2023-04-11 | | Release date: | 2024-07-03 | | Last modified: | 2025-01-22 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Cas12a domain flexibility guides R-loop formation and forces RuvC resetting.
Mol.Cell, 84, 2024
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8SFL
 | | WT CRISPR-Cas12a with a 15bp R-loop | | Descriptor: | CRISPR-associated endonuclease Cas12a, DNA (40-MER), RNA (34-MER) | | Authors: | Strohkendl, I, Taylor, D.W. | | Deposit date: | 2023-04-11 | | Release date: | 2024-07-03 | | Last modified: | 2025-01-22 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Cas12a domain flexibility guides R-loop formation and forces RuvC resetting.
Mol.Cell, 84, 2024
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8SFP
 | | WT CRISPR-Cas12a with the target strand in the RuvC active site. | | Descriptor: | CRISPR-associated endonuclease Cas12a, DNA (40-MER), DNA (5'-D(P*CP*TP*TP*CP*CP*GP*AP*TP*CP*TP*TP*TP*TP*AP*GP*TP*GP*AP*TP*A)-3'), ... | | Authors: | Strohkendl, I, Taylor, D.W. | | Deposit date: | 2023-04-11 | | Release date: | 2024-07-03 | | Last modified: | 2025-01-22 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Cas12a domain flexibility guides R-loop formation and forces RuvC resetting.
Mol.Cell, 84, 2024
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