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Crystal structure of EGFR kinase domain (L858R, T790M, V948R) in complex with the covalent inhibitor CO-1686
Descriptor:	Epidermal growth factor receptor, N-(3-{[2-{[4-(4-acetylpiperazin-1-yl)-2-methoxyphenyl]amino}-5-(trifluoromethyl)pyrimidin-4-yl]amino}phenyl)propanamide
Authors:	Gajiwala, K.S, Ferre, R.A.
Deposit date:	2017-02-21
Release date:	2017-10-18
Last modified:	2017-11-29
Method:	X-RAY DIFFRACTION (3.06 Å)
Cite:	Proteome-wide Map of Targets of T790M-EGFR-Directed Covalent Inhibitors. Cell Chem Biol, 24, 2017