9IP8
 
 | | Poly-alanine model for HL-type bispecific diabody Ex3 composed of 528 and OKT3 Fvs in ternary complex with sEGFR and CD3gamma-epsilon (closed conformation) | | Descriptor: | Epidermal growth factor receptor, HL-type bispecific diabody Ex3, T-cell surface glycoprotein CD3 gamma chain,T-cell surface glycoprotein CD3 epsilon chain | | Authors: | Sato, K, Uehara, S, Tsugita, A, Matsui, T, Asano, R, Makabe, K, Yokoyama, T, Tanaka, Y. | | Deposit date: | 2024-07-10 | | Release date: | 2025-05-28 | | Last modified: | 2025-08-06 | | Method: | ELECTRON MICROSCOPY (3.91 Å) | | Cite: | Bispecific antibody-antigen complex structures reveal activity enhancement by domain rearrangement.
Cell Rep, 44, 2025
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9IPD
 | | Poly-alanine model for LH-type bispecific diabody Ex3 composed of 528 and OKT3 Fvs in ternary complex with sEGFR and CD3gamma-epsilon (middle conformation) | | Descriptor: | Epidermal growth factor receptor, LH-type bispecific diabody Ex3, T-cell surface glycoprotein CD3 gamma chain,T-cell surface glycoprotein CD3 epsilon chain | | Authors: | Sato, K, Uehara, S, Tsugita, A, Matsui, T, Asano, R, Makabe, K, Yokoyama, T, Tanaka, Y. | | Deposit date: | 2024-07-10 | | Release date: | 2025-05-28 | | Last modified: | 2025-08-06 | | Method: | ELECTRON MICROSCOPY (3.29 Å) | | Cite: | Bispecific antibody-antigen complex structures reveal activity enhancement by domain rearrangement.
Cell Rep, 44, 2025
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9IP7
 | | Local refinement structure of sEGFR and 528 Fv (from HL-type bispecific diabody Ex3) complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 528 Fv from HL-type bispecific diabody Ex3, ... | | Authors: | Sato, K, Uehara, S, Tsugita, A, Matsui, T, Asano, R, Makabe, K, Yokoyama, T, Tanaka, Y. | | Deposit date: | 2024-07-10 | | Release date: | 2025-05-28 | | Last modified: | 2025-08-06 | | Method: | ELECTRON MICROSCOPY (3.21 Å) | | Cite: | Bispecific antibody-antigen complex structures reveal activity enhancement by domain rearrangement.
Cell Rep, 44, 2025
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9IPC
 | | Poly-alanine model for LH-type bispecific diabody Ex3 composed of 528 and OKT3 Fvs in ternary complex with sEGFR and CD3gamma-epsilon (closed conformation) | | Descriptor: | Epidermal growth factor receptor, LH-type bispecific diabody Ex3, T-cell surface glycoprotein CD3 gamma chain,T-cell surface glycoprotein CD3 epsilon chain | | Authors: | Sato, K, Uehara, S, Tsugita, A, Matsui, T, Asano, R, Makabe, K, Yokoyama, T, Tanaka, Y. | | Deposit date: | 2024-07-10 | | Release date: | 2025-05-28 | | Last modified: | 2025-08-06 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Bispecific antibody-antigen complex structures reveal activity enhancement by domain rearrangement.
Cell Rep, 44, 2025
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9IPE
 | | Poly-alanine model for LH-type bispecific diabody Ex3 composed of 528 and OKT3 Fvs in ternary complex with sEGFR and CD3gamma-epsilon (open conformation) | | Descriptor: | Epidermal growth factor receptor, LH-type bispecific diabody Ex3, T-cell surface glycoprotein CD3 gamma chain,T-cell surface glycoprotein CD3 epsilon chain | | Authors: | Sato, K, Uehara, S, Tsugita, A, Matsui, T, Asano, R, Makabe, K, Yokoyama, T, Tanaka, Y. | | Deposit date: | 2024-07-10 | | Release date: | 2025-05-28 | | Last modified: | 2025-08-06 | | Method: | ELECTRON MICROSCOPY (3.31 Å) | | Cite: | Bispecific antibody-antigen complex structures reveal activity enhancement by domain rearrangement.
Cell Rep, 44, 2025
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9IP9
 | | Poly-alanine model for HL-type bispecific diabody Ex3 composed of 528 and OKT3 Fvs in ternary complex with sEGFR and CD3gamma-epsilon (middle conformation) | | Descriptor: | Epidermal growth factor receptor, HL-type bispecific diabody Ex3, T-cell surface glycoprotein CD3 gamma chain,T-cell surface glycoprotein CD3 epsilon chain | | Authors: | Sato, K, Uehara, S, Tsugita, A, Matsui, T, Asano, R, Makabe, K, Yokoyama, T, Tanaka, Y. | | Deposit date: | 2024-07-10 | | Release date: | 2025-05-28 | | Last modified: | 2025-08-06 | | Method: | ELECTRON MICROSCOPY (3.64 Å) | | Cite: | Bispecific antibody-antigen complex structures reveal activity enhancement by domain rearrangement.
Cell Rep, 44, 2025
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9IPA
 | | Poly-alanine model for HL-type bispecific diabody Ex3 composed of 528 and OKT3 Fvs in ternary complex with sEGFR and CD3gamma-epsilon (open conformation) | | Descriptor: | Epidermal growth factor receptor, HL-type bispecific diabody Ex3, T-cell surface glycoprotein CD3 gamma chain,T-cell surface glycoprotein CD3 epsilon chain | | Authors: | Sato, K, Uehara, S, Tsugita, A, Matsui, T, Asano, R, Makabe, K, Yokoyama, T, Tanaka, Y. | | Deposit date: | 2024-07-10 | | Release date: | 2025-05-28 | | Last modified: | 2025-08-06 | | Method: | ELECTRON MICROSCOPY (3.85 Å) | | Cite: | Bispecific antibody-antigen complex structures reveal activity enhancement by domain rearrangement.
Cell Rep, 44, 2025
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9IPB
 | | Local refinement structure of sEGFR and 528 Fv (from LH-type bispecific diabody Ex3) complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 528 Fv from LH-type bispecific diabody Ex3, ... | | Authors: | Sato, K, Uehara, S, Tsugita, A, Matsui, T, Asano, R, Makabe, K, Yokoyama, T, Tanaka, Y. | | Deposit date: | 2024-07-10 | | Release date: | 2025-05-28 | | Last modified: | 2025-08-06 | | Method: | ELECTRON MICROSCOPY (2.93 Å) | | Cite: | Bispecific antibody-antigen complex structures reveal activity enhancement by domain rearrangement.
Cell Rep, 44, 2025
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