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PDB: 1 results

8C12
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BU of 8c12 by Molmil
Identification of an intermediate activation state of PAK5 reveals a novel mechanism of kinase inhibition.
Descriptor: PAK5-Af17, Serine/threonine-protein kinase PAK 5
Authors:Martin, H.L, Turner, A.L, Trinh, C.H, Bayliss, R.W, Tomlinson, D.C.
Deposit date:2022-12-19
Release date:2023-10-25
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.549 Å)
Cite:Affimer-mediated locking of p21-activated kinase 5 in an intermediate activation state results in kinase inhibition.
Cell Rep, 42, 2023

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