9B4F
| Structure of human PSS1-P269S | Descriptor: | CALCIUM ION, Phosphatidylserine synthase 1 | Authors: | Long, T, Li, X. | Deposit date: | 2024-03-20 | Release date: | 2024-09-04 | Last modified: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (3.27 Å) | Cite: | Molecular insights into human phosphatidylserine synthase 1 reveal its inhibition promotes LDL uptake. Cell, 2024
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9B4E
| Structure of wild type human PSS1 | Descriptor: | (2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dihexadecanoate, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CALCIUM ION, ... | Authors: | Long, T, Li, X. | Deposit date: | 2024-03-20 | Release date: | 2024-09-04 | Last modified: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Molecular insights into human phosphatidylserine synthase 1 reveal its inhibition promotes LDL uptake. Cell, 2024
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9B4G
| Structure of inhibitor-bound human PSS1 | Descriptor: | (2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dihexadecanoate, (7P)-7-[(4S)-4-{4-[3,5-bis(trifluoromethyl)phenoxy]phenyl}-5-(2,2-difluoropropyl)-6-oxo-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl]-1,3-benzoxazol-2(3H)-one, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, ... | Authors: | Long, T, Li, X. | Deposit date: | 2024-03-20 | Release date: | 2024-09-04 | Last modified: | 2024-09-11 | Method: | ELECTRON MICROSCOPY (2.87 Å) | Cite: | Molecular insights into human phosphatidylserine synthase 1 reveal its inhibition promotes LDL uptake. Cell, 2024
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