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Crystal structure of EGFR double mutant (T790M/L858R) in complex with compound 6.
Descriptor:	2-[2-(3-methoxyphenyl)pyrimidin-4-yl]-1'-prop-2-enoyl-spiro[5,6-dihydro-1~{H}-pyrrolo[3,2-c]pyridine-7,4'-piperidine]-4-one, Epidermal growth factor receptor
Authors:	Collie, G.W.
Deposit date:	2021-06-22
Release date:	2021-10-20
Method:	X-RAY DIFFRACTION (2.56 Å)
Cite:	Discovery and optimization of covalent EGFR T790M/L858R mutant inhibitors". Bioorg.Med.Chem.Lett., 2021

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PDB entries from 2024-07-24