PDB Search results for query - Protein Data Bank Japan

PDB: 3 results

Humanized yeast ACC carboxyltransferase domain bound to 6,7-dimethyl-1'-[(7-methyl-1H-indazol-5-yl)carbonyl]spiro[chromene-2,4'-piperidin]-4(3H)-one
Descriptor:	6,7-dimethyl-1'-[(7-methyl-1H-indazol-5-yl)carbonyl]spiro[chromene-2,4'-piperidin]-4(3H)-one, Acetyl-CoA carboxylase, SULFATE ION
Authors:	Vajdos, F.F.
Deposit date:	2015-07-23
Release date:	2015-10-14
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Discovery of spirocyclic-diamine inhibitors of mammalian acetyl CoA-carboxylase. Bioorg.Med.Chem.Lett., 25, 2015

Humanized yeast ACC carboxyltransferase domain bound to 2,2-dimethylpropyl (1S)-1-methyl-8-[(7-methyl-1H-indazol-5-yl)carbonyl]-2,8-diazaspiro[4.5]decane-2-carboxylate
Descriptor:	2,2-dimethylpropyl (1S)-1-methyl-8-[(7-methyl-1H-indazol-5-yl)carbonyl]-2,8-diazaspiro[4.5]decane-2-carboxylate, Acetyl-CoA carboxylase, SULFATE ION
Authors:	Vajdos, F.F.
Deposit date:	2015-07-23
Release date:	2015-10-14
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (2.34 Å)
Cite:	Discovery of spirocyclic-diamine inhibitors of mammalian acetyl CoA-carboxylase. Bioorg.Med.Chem.Lett., 25, 2015

Humanized yeast ACC carboxyltransferase domain bound to tert-butyl 7-[(7-methyl-1H-indazol-5-yl)carbonyl]-2,7-diazaspiro[3.5]nonane-2-carboxylate
Descriptor:	Acetyl-CoA carboxylase, SULFATE ION, tert-butyl 7-[(7-methyl-1H-indazol-5-yl)carbonyl]-2,7-diazaspiro[3.5]nonane-2-carboxylate
Authors:	Vajdos, F.F.
Deposit date:	2015-07-23
Release date:	2015-10-14
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (2.7 Å)
Cite:	Discovery of spirocyclic-diamine inhibitors of mammalian acetyl CoA-carboxylase. Bioorg.Med.Chem.Lett., 25, 2015