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PDB: 3 results

4U44
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BU of 4u44 by Molmil
MAP4K4 in complex with inhibitor (compound 16)
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-phenyl-N-(pyridin-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine, Mitogen-activated protein kinase kinase kinase kinase 4, ...
Authors:Harris, S.F, Wu, P, Coons, M.
Deposit date:2014-07-23
Release date:2014-09-03
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Fragment-based identification and optimization of a class of potent pyrrolo[2,1-f][1,2,4]triazine MAP4K4 inhibitors.
Bioorg.Med.Chem.Lett., 24, 2014
4U43
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BU of 4u43 by Molmil
MAP4K4 in complex with inhibitor (compound 6)
Descriptor: Mitogen-activated protein kinase kinase kinase kinase 4, N-(pyridin-3-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine
Authors:Harris, S.F, Wu, P, Coons, M.
Deposit date:2014-07-23
Release date:2014-09-03
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Fragment-based identification and optimization of a class of potent pyrrolo[2,1-f][1,2,4]triazine MAP4K4 inhibitors.
Bioorg.Med.Chem.Lett., 24, 2014
4U45
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BU of 4u45 by Molmil
MAP4K4 in complex with inhibitor (compound 25)
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-(1H-pyrazol-4-yl)-N-(pyridin-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine, MAGNESIUM ION, ...
Authors:Harris, S.F, Wu, P, Coons, M.
Deposit date:2014-07-23
Release date:2014-09-03
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Fragment-based identification and optimization of a class of potent pyrrolo[2,1-f][1,2,4]triazine MAP4K4 inhibitors.
Bioorg.Med.Chem.Lett., 24, 2014

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