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Crystal Structure of Human Beta-Tryptase Complexed with a Synthetic Inhibitor with a Tropanylamide Scaffold
Descriptor:	CARBONATE ION, TPSB2 protein, {(3-exo)-3-[5-(aminomethyl)-2-fluorophenyl]-8-azabicyclo[3.2.1]oct-8-yl}(4-bromo-3-methyl-5-propoxythiophen-2-yl)methanone
Authors:	Zhang, Y, Colonna, C, Michot, N.
Deposit date:	2011-12-22
Release date:	2012-03-14
Last modified:	2017-11-08
Method:	X-RAY DIFFRACTION (2.09 Å)
Cite:	A beta-tryptase inhibitor with a tropanylamide scaffold to improve in vitro stability and to lower hERG channel binding affinity Bioorg.Med.Chem.Lett., 22, 2012