PDB Search results for query - Protein Data Bank Japan

PDB: 3 results

Cathepsin K in complex with a selective 2-cyano-pyrimidine inhibitor
Descriptor:	4-cycloheptyl-6-(3-piperidin-1-ylpropyl)pyrimidine-2-carbonitrile, Cathepsin K, SULFATE ION
Authors:	Fradera, X, Uitdehaag, J.C.M, van Zeeland, M.
Deposit date:	2009-12-02
Release date:	2010-03-02
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (1.51 Å)
Cite:	Design and optimization of a series of novel 2-cyano-pyrimidines as cathepsin K inhibitors Bioorg.Med.Chem.Lett., 20, 2010

X-ray structure of Cathepsin K covalently bound to a triazine ligand
Descriptor:	4-(cyclohexylamino)-6-piperazin-1-yl-1,3,5-triazine-2-carbonitrile, Cathepsin K, trifluoroacetic acid
Authors:	Uitdehaag, J.C.M, van Zeeland, M.
Deposit date:	2009-12-01
Release date:	2010-03-02
Last modified:	2017-11-01
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Design and optimization of a series of novel 2-cyano-pyrimidines as cathepsin K inhibitors. Bioorg.Med.Chem.Lett., 20, 2010

Cathepsin K in complex with a non-selective 2-cyano-pyrimidine inhibitor
Descriptor:	4-(3-piperidin-1-ylpropyl)-6-[3-(trifluoromethyl)phenyl]pyrimidine-2-carbonitrile, Cathepsin K, SULFATE ION
Authors:	Fradera, X, Uitdehaag, J.C.M, van Zeeland, M.
Deposit date:	2009-12-02
Release date:	2010-03-02
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (1.49 Å)
Cite:	Design and optimization of a series of novel 2-cyano-pyrimidines as cathepsin K inhibitors Bioorg.Med.Chem.Lett., 20, 2010