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Crystal Structure of 11beta-HSD1 Double Mutant (L262R, F278E) Complexed with (3,3-dimethylpiperidin-1-yl)(6-(3-fluoro-4-methylphenyl)pyridin-2-yl)methanone
Descriptor:	(3,3-dimethylpiperidin-1-yl)(6-(3-fluoro-4-methylphenyl)pyridin-2-yl)methanone, Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:	Sheriff, S.
Deposit date:	2008-03-07
Release date:	2008-06-10
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (2.35 Å)
Cite:	Pyridine amides as potent and selective inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 Bioorg.Med.Chem.Lett., 18, 2008