2AMP
| Crystal Structure Of Porcine Transmissible Gastroenteritis Virus Mpro in Complex with an Inhibitor N1 | Descriptor: | 3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]-L-ALANYL-L-VALYL-N~1~-((1S)-4-ETHOXY-4-OXO-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE | Authors: | Yang, H, Xue, X, Yang, K, Zhao, Q, Bartlam, M, Rao, Z. | Deposit date: | 2005-08-10 | Release date: | 2005-09-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases. Plos Biol., 3, 2005
|
|
2AMQ
| Crystal Structure Of SARS_CoV Mpro in Complex with an Inhibitor N3 | Descriptor: | 3C-like proteinase, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE | Authors: | Yang, H, Xue, X, Yang, K, Zhao, Q, Bartlam, M, Rao, Z. | Deposit date: | 2005-08-10 | Release date: | 2005-09-13 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases. Plos Biol., 3, 2005
|
|
2AMS
| Structure of the oxidized Hipip from thermochromatium tepidum at 1.4 angstrom resolution | Descriptor: | GLYCEROL, High potential iron-sulfur protein, IRON/SULFUR CLUSTER, ... | Authors: | Hunsicker-Wang, L.M, Han, W, Stout, C.D, Noodleman, L, Fee, J.A. | Deposit date: | 2005-08-10 | Release date: | 2006-08-15 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Geometric factors determine, in part, the electronic state of the 4Fe-4S cluster of Hipip from thermochromtium tepidum: a geomteric, crystallographic, and theoretical study. To be Published
|
|
2AMT
| Structure of 2C-Methyl-D-Erythritol 2,4-Clycodiphosphate Synthase complexed with a CDP derived fluorescent inhibitor | Descriptor: | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, 5'-O-[({[(2-{[(2-AMINOPHENYL)CARBONYL]OXY}ETHYL)OXY]PHOSPHINATO}OXY)PHOSPHINATO]CYTIDINE, GERANYL DIPHOSPHATE, ... | Authors: | Ramsden, N.L, Hunter, W.N. | Deposit date: | 2005-08-10 | Release date: | 2006-02-28 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Fluorescent Inhibitors for IspF, an Enzyme in the Non-Mevalonate Pathway for Isoprenoid Biosynthesis and a Potential Target for Antimalarial Therapy. Angew.Chem.Int.Ed.Engl., 45, 2006
|
|
2AMU
| |
2AMV
| THE STRUCTURE OF GLYCOGEN PHOSPHORYLASE B WITH AN ALKYL-DIHYDROPYRIDINE-DICARBOXYLIC ACID | Descriptor: | 2,3-DICARBOXY-4-(2-CHLORO-PHENYL)-1-ETHYL-5-ISOPROPOXYCARBONYL-6-METHYL-PYRIDINIUM, GLYCEROL, PROTEIN (GLYCOGEN PHOSPHORYLASE), ... | Authors: | Zographos, S.E, Oikonomakos, N.G, Johnson, L.N. | Deposit date: | 1998-10-13 | Release date: | 1998-10-21 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The structure of glycogen phosphorylase b with an alkyldihydropyridine-dicarboxylic acid compound, a novel and potent inhibitor. Structure, 5, 1997
|
|
2AMX
| Crystal structure of Plasmodium Yoelii Adenosine deaminase (PY02076) | Descriptor: | COBALT (II) ION, UNKNOWN ATOM OR ION, adenosine deaminase | Authors: | Dong, A, Vedadi, M, Wasney, G, Zhao, Y, Lew, J, Alam, Z, Melone, M, Koeieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Amani, M, Structural Genomics Consortium (SGC) | Deposit date: | 2005-08-10 | Release date: | 2005-09-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms. Mol.Biochem.Parasitol., 151, 2007
|
|
2AMY
| X-Ray Structure of Human Phosphomannomutase 2 (PMM2) | Descriptor: | 1,2-ETHANEDIOL, GLYCINE, Phosphomannomutase 2 | Authors: | Wesenberg, G.E, Phillips Jr, G.N, McCoy, J.G, Bitto, E, Bingman, C.A, Allard, S.T.M, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2005-08-10 | Release date: | 2005-08-23 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | X-Ray Structure of Human Phosphomannomutase 2 (PMM2) To be Published
|
|
2AN0
| |
2AN1
| Structural Genomics, The crystal structure of a putative kinase from Salmonella typhimurim LT2 | Descriptor: | putative kinase | Authors: | Zhang, R, Zhou, M, Holzle, D, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-08-10 | Release date: | 2005-09-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The crystal structure of a putative kinase from Salmonella typhimurim LT2 To be Published
|
|
2AN2
| P332G, A333S Double mutant of the Bacillus subtilis Nitric Oxide Synthase | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, ARGININE, P332G A333S double mutant of Nitric Oxide Synthase from Bacillus subtilis, ... | Authors: | Pant, K, Crane, B.R. | Deposit date: | 2005-08-11 | Release date: | 2006-08-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of a loose dimer: an intermediate in nitric oxide synthase assembly J.Mol.Biol., 352, 2005
|
|
2AN3
| Structure of PNMT with S-adenosyl-L-homocysteine and the semi-rigid analogue acceptor substrate cis-(1R,2S)-2-amino-1-tetralol. | Descriptor: | CIS-(1R,2S)-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL, Phenylethanolamine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Gee, C.L, Tyndall, J.D.A, Grunewald, G.L, Wu, Q, McLeish, M.J, Martin, J.L. | Deposit date: | 2005-08-11 | Release date: | 2006-03-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Mode of binding of methyl acceptor substrates to the adrenaline-synthesizing enzyme phenylethanolamine N-methyltransferase: implications for catalysis Biochemistry, 44, 2005
|
|
2AN4
| Structure of PNMT complexed with S-adenosyl-L-homocysteine and the acceptor substrate octopamine | Descriptor: | 4-(2R-AMINO-1-HYDROXYETHYL)PHENOL, PHOSPHATE ION, Phenylethanolamine N-methyltransferase, ... | Authors: | Gee, C.L, Tyndall, J.D.A, Grunewald, G.L, Wu, Q, McLeish, M.J, Martin, J.L. | Deposit date: | 2005-08-11 | Release date: | 2006-03-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Mode of binding of methyl acceptor substrates to the adrenaline-synthesizing enzyme phenylethanolamine N-methyltransferase: implications for catalysis Biochemistry, 44, 2005
|
|
2AN5
| Structure of human PNMT complexed with S-adenosyl-homocysteine and an inhibitor, trans-(1S,2S)-2-amino-1-tetralol | Descriptor: | PHOSPHATE ION, Phenylethanolamine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Gee, C.L, Tyndall, J.D.A, Grunewald, G.L, Wu, Q, McLeish, M.J, Martin, J.L. | Deposit date: | 2005-08-11 | Release date: | 2006-03-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Mode of binding of methyl acceptor substrates to the adrenaline-synthesizing enzyme phenylethanolamine N-methyltransferase: implications for catalysis Biochemistry, 44, 2005
|
|
2AN6
| Protein-peptide complex | Descriptor: | Ubiquitin ligase SIAH1A, ZINC ION, peptide from Phyllopod | Authors: | House, C.M, Hancock, N.C, Moller, A, Cromer, B.A, Fedorov, V, Bowtell, D.D.L, Parker, M.W, Polekhina, G. | Deposit date: | 2005-08-11 | Release date: | 2006-05-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Elucidation of the substrate binding site of Siah ubiquitin ligase Structure, 14, 2006
|
|
2AN7
| Solution structure of the bacterial antidote ParD | Descriptor: | Protein parD | Authors: | Oberer, M, Zangger, K, Gruber, K, Keller, W. | Deposit date: | 2005-08-11 | Release date: | 2006-09-05 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The solution structure of ParD, the antidote of the ParDE toxin antitoxin module, provides the structural basis for DNA and toxin binding. Protein Sci., 16, 2007
|
|
2AN9
| Crystal Structure Of Oligomeric E.coli Guanylate Kinase In Complex With GDP | Descriptor: | GUANOSINE, GUANOSINE-5'-DIPHOSPHATE, Guanylate kinase, ... | Authors: | Hible, G, Renault, L, Schaeffer, F, Christova, P, Radulescu, A.Z, Evrin, C, Gilles, A.M, Cherfils, J. | Deposit date: | 2005-08-11 | Release date: | 2005-08-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Calorimetric and crystallographic analysis of the oligomeric structure of Escherichia coli GMP kinase J.Mol.Biol., 352, 2005
|
|
2ANA
| |
2ANB
| Crystal Structure Of Oligomeric E.coli Guanylate Kinase In Complex With GMP | Descriptor: | GUANOSINE-5'-MONOPHOSPHATE, Guanylate kinase, SULFATE ION | Authors: | Hible, G, Renault, L, Schaeffer, F, Christova, P, Radulescu, A.Z, Evrin, C, Gilles, A.M, Cherfils, J. | Deposit date: | 2005-08-11 | Release date: | 2005-08-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Calorimetric and crystallographic analysis of the oligomeric structure of Escherichia coli GMP kinase J.Mol.Biol., 352, 2005
|
|
2ANC
| Crystal Structure Of Unliganded Form Of Oligomeric E.coli Guanylate Kinase | Descriptor: | Guanylate kinase | Authors: | Hible, G, Renault, L, Schaeffer, F, Christova, P, Radulescu, A.Z, Evrin, C, Gilles, A.M, Cherfils, J. | Deposit date: | 2005-08-11 | Release date: | 2005-08-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Calorimetric and crystallographic analysis of the oligomeric structure of Escherichia coli GMP kinase J.Mol.Biol., 352, 2005
|
|
2ANE
| Crystal structure of N-terminal domain of E.Coli Lon Protease | Descriptor: | ATP-dependent protease La | Authors: | Li, M, Rasulova, F, Melnikov, E.E, Rotanova, T.V, Gustchina, A, Maurizi, M.R, Wlodawer, A. | Deposit date: | 2005-08-11 | Release date: | 2005-11-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Crystal structure of the N-terminal domain of E. coli Lon protease. Protein Sci., 14, 2005
|
|
2ANG
| CRYSTAL STRUCTURE OF HUMAN ANGIOGENIN OF THE MET(-1) FORM | Descriptor: | ANGIOGENIN, CITRIC ACID | Authors: | Leonidas, D.D, Allen, S.C, Acharya, K.R. | Deposit date: | 1998-11-12 | Release date: | 1999-04-02 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Refined crystal structures of native human angiogenin and two active site variants: implications for the unique functional properties of an enzyme involved in neovascularisation during tumour growth. J.Mol.Biol., 285, 1999
|
|
2ANH
| ALKALINE PHOSPHATASE (D153H) | Descriptor: | ALKALINE PHOSPHATASE, PHOSPHATE ION, ZINC ION | Authors: | Murphy, J.E, Tibbitts, T.T, Kantrowitz, E.R. | Deposit date: | 1995-09-06 | Release date: | 1996-01-29 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Mutations at positions 153 and 328 in Escherichia coli alkaline phosphatase provide insight towards the structure and function of mammalian and yeast alkaline phosphatases. J.Mol.Biol., 253, 1995
|
|
2ANI
| Crystal structure of the F127Y mutant of Ribonucleotide Reductase R2 from Chlamydia trachomatis | Descriptor: | FE (III) ION, LEAD (II) ION, Ribonucleoside-diphosphate reductase beta subunit | Authors: | Hogbom, M, Stenmark, P, Nordlund, P. | Deposit date: | 2005-08-11 | Release date: | 2006-07-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of the high-valent FeIIIFeIV state in ribonucleotide reductase (RNR) of Chlamydia trachomatis--combined EPR, 57Fe-, 1H-ENDOR and X-ray studies. Biochim.Biophys.Acta, 1774, 2007
|
|
2ANJ
| Crystal Structure of the Glur2 Ligand Binding Core (S1S2J-Y450W) Mutant in Complex With the Partial Agonist Kainic Acid at 2.1 A Resolution | Descriptor: | 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 2 | Authors: | Holm, M.M, Naur, P, Vestergaard, B, Geballe, M.T, Gajhede, M, Kastrup, J.S, Traynelis, S.F, Egebjerg, J. | Deposit date: | 2005-08-11 | Release date: | 2005-08-30 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A Binding Site Tyrosine Shapes Desensitization Kinetics and Agonist Potency at GluR2: a mutagenic, kinetic, and crystallographic study J.Biol.Chem., 280, 2005
|
|