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1D1N
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BU of 1d1n by Molmil
SOLUTION STRUCTURE OF THE FMET-TRNAFMET BINDING DOMAIN OF BECILLUS STEAROTHERMOPHILLUS TRANSLATION INITIATION FACTOR IF2
Descriptor: INITIATION FACTOR 2
Authors:Meunier, S, Spurio, S, Czisch, M, Wechselberger, R, Gueunneugues, M.
Deposit date:1999-09-20
Release date:2000-09-20
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of the fMet-tRNA(fMet)-binding domain of B. stearothermophilus initiation factor IF2.
EMBO J., 19, 2000
3E1Y
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BU of 3e1y by Molmil
Crystal structure of human eRF1/eRF3 complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, Eukaryotic peptide chain release factor subunit 1
Authors:Cheng, Z, Lim, M, Kong, C, Song, H.
Deposit date:2008-08-05
Release date:2009-05-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural insights into eRF3 and stop codon recognition by eRF1
Genes Dev., 23, 2009
4V9J
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BU of 4v9j by Molmil
70S ribosome translocation intermediate GDPNP-II containing elongation factor EFG/GDPNP, mRNA, and tRNA bound in the pe*/E state.
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Zhou, J, Lancaster, L, Donohue, J.P, Noller, H.F.
Deposit date:2013-04-23
Release date:2014-07-09
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (3.86 Å)
Cite:Crystal structures of EF-G-ribosome complexes trapped in intermediate states of translocation.
Science, 340, 2013
5OT7
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BU of 5ot7 by Molmil
Elongation factor G-ribosome complex captures in the absence of inhibitors.
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Mace, K, Giudice, E, Chat, S, Gillet, R.
Deposit date:2017-08-21
Release date:2018-02-14
Last modified:2018-04-11
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:The structure of an elongation factor G-ribosome complex captured in the absence of inhibitors.
Nucleic Acids Res., 46, 2018
7O9K
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BU of 7o9k by Molmil
Human mitochondrial ribosome large subunit assembly intermediate with MTERF4-NSUN4, MRM2, MTG1, the MALSU module, GTPBP5 and mtEF-Tu
Descriptor: 16S rRNA, 39S ribosomal protein L10, mitochondrial, ...
Authors:Valentin Gese, G, Hallberg, B.M.
Deposit date:2021-04-16
Release date:2021-06-30
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for late maturation steps of the human mitoribosomal large subunit.
Nat Commun, 12, 2021
2RDO
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BU of 2rdo by Molmil
50S subunit with EF-G(GDPNP) and RRF bound
Descriptor: 23S RIBOSOMAL RNA, 50S ribosomal protein L1, 50S ribosomal protein L11, ...
Authors:Gao, N, Zavialov, A.V, Ehrenberg, M, Frank, J.
Deposit date:2007-09-24
Release date:2008-03-04
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (9.1 Å)
Cite:Specific interaction between EF-G and RRF and its implication for GTP-dependent ribosome splitting into subunits.
J.Mol.Biol., 374, 2007
5TY0
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BU of 5ty0 by Molmil
2.22 Angstrom Crystal Structure of N-terminal Fragment (residues 1-419) of Elongation Factor G from Legionella pneumophila.
Descriptor: Elongation factor G, SODIUM ION, beta-D-glucopyranose
Authors:Minasov, G, Wawrzak, Z, Shuvalova, L, Cardona-Correa, A, Dubrovska, I, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2016-11-17
Release date:2016-11-30
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:2.22 Angstrom Crystal Structure of N-terminal Fragment (residues 1-419) of Elongation Factor G from Legionella pneumophila.
To Be Published
9BDP
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BU of 9bdp by Molmil
80S ribosome bound with angiogenin and complex of eEF1A and Ala-tRNAAla
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Loveland, A.B, Korostelev, A.A.
Deposit date:2024-04-12
Release date:2024-07-24
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural mechanism of angiogenin activation by the ribosome.
Nature, 630, 2024
9FMD
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BU of 9fmd by Molmil
Integrative model of the human post-catalytic spliceosome (P-complex)
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ...
Authors:Rothe, P, Plaschka, C, Vorlaender, M.K.
Deposit date:2024-06-05
Release date:2024-07-10
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mechanism for the initiation of spliceosome disassembly.
Nature, 2024
6VLZ
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BU of 6vlz by Molmil
Structure of the human mitochondrial ribosome-EF-G1 complex (ClassI)
Descriptor: 12s rRNA, 16s rRNA, 28S ribosomal protein S10, ...
Authors:Sharma, M.R, Koripella, R.K, Agrawal, R.K.
Deposit date:2020-01-27
Release date:2020-08-05
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Structures of the human mitochondrial ribosome bound to EF-G1 reveal distinct features of mitochondrial translation elongation.
Nat Commun, 11, 2020
6FEC
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BU of 6fec by Molmil
Human cap-dependent 48S pre-initiation complex
Descriptor: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
Authors:Schaffitzel, C, Schaffitzel, C.
Deposit date:2017-12-31
Release date:2018-03-14
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (6.3 Å)
Cite:Structure of a human cap-dependent 48S translation pre-initiation complex.
Nucleic Acids Res., 46, 2018
7F67
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BU of 7f67 by Molmil
eIF2B-SFSV NSs-2-eIF2
Descriptor: Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, Non-structural protein NS-S, ...
Authors:Kashiwagi, K, Ito, T.
Deposit date:2021-06-24
Release date:2021-12-01
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.59 Å)
Cite:eIF2B-capturing viral protein NSs suppresses the integrated stress response.
Nat Commun, 12, 2021
7F66
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BU of 7f66 by Molmil
eIF2B-SFSV NSs-1-eIF2
Descriptor: Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, Non-structural protein NS-S, ...
Authors:Kashiwagi, K, Ito, T.
Deposit date:2021-06-24
Release date:2021-12-01
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:eIF2B-capturing viral protein NSs suppresses the integrated stress response.
Nat Commun, 12, 2021
6FF4
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BU of 6ff4 by Molmil
human Bact spliceosome core structure
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ...
Authors:Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H.
Deposit date:2018-01-03
Release date:2018-08-29
Last modified:2020-10-07
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure and Conformational Dynamics of the Human Spliceosomal BactComplex.
Cell, 172, 2018
6VMI
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BU of 6vmi by Molmil
Structure of the human mitochondrial ribosome-EF-G1 complex (ClassIII)
Descriptor: 12s rRNA, 16s rRNA, 28S ribosomal protein S10, ...
Authors:Sharma, M.R, Koripella, R.K, Agrawal, R.K.
Deposit date:2020-01-28
Release date:2020-08-05
Last modified:2021-02-17
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Structures of the human mitochondrial ribosome bound to EF-G1 reveal distinct features of mitochondrial translation elongation.
Nat Commun, 11, 2020
8HL2
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BU of 8hl2 by Molmil
Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome
Descriptor: 16s rRNA (1493-MER), 23s rRNA (3000-MER), 30S ribosomal protein S10, ...
Authors:Wang, Y.H, Zhou, J.
Deposit date:2022-11-28
Release date:2023-09-20
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Cryo-electron microscopy structure and translocation mechanism of the crenarchaeal ribosome.
Nucleic Acids Res., 51, 2023
8HL3
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BU of 8hl3 by Molmil
Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome
Descriptor: 16s rRNA (1493-MER), 23s rRNA (3000-MER), 30S ribosomal protein S10, ...
Authors:Wang, Y.H, Zhou, J.
Deposit date:2022-11-28
Release date:2023-09-20
Last modified:2024-04-03
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Cryo-electron microscopy structure and translocation mechanism of the crenarchaeal ribosome.
Nucleic Acids Res., 51, 2023
1AIP
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BU of 1aip by Molmil
EF-TU EF-TS COMPLEX FROM THERMUS THERMOPHILUS
Descriptor: ELONGATION FACTOR TS, ELONGATION FACTOR TU
Authors:Wang, Y, Jiang, Y, Meyering-Voss, M, Sprinzl, M, Sigler, P.B.
Deposit date:1997-04-22
Release date:1997-10-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the EF-Tu.EF-Ts complex from Thermus thermophilus.
Nat.Struct.Biol., 4, 1997
1B23
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BU of 1b23 by Molmil
E. coli cysteinyl-tRNA and T. aquaticus elongation factor EF-TU:GTP ternary complex
Descriptor: CYSTEINE, CYSTEINYL TRNA, ELONGATION FACTOR TU, ...
Authors:Nissen, P, Kjeldgaard, M, Thirup, S, Nyborg, J.
Deposit date:1998-12-04
Release date:1998-12-07
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The crystal structure of Cys-tRNACys-EF-Tu-GDPNP reveals general and specific features in the ternary complex and in tRNA.
Structure Fold.Des., 7, 1999
7UG7
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BU of 7ug7 by Molmil
70S ribosome complex in an intermediate state of translocation bound to EF-G(GDP) stalled by Argyrin B
Descriptor: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ...
Authors:Rundlet, E.J, Wieland, M, Holm, M, Koller, T.O, Blanchard, S.C, Wilson, D.N.
Deposit date:2022-03-24
Release date:2022-05-18
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (2.58 Å)
Cite:The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VMC
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BU of 7vmc by Molmil
Crystal structure of EF-Tu/CdiA/CdiI
Descriptor: Contact-dependent inhibitor I, Elongation factor Tu, tRNA nuclease CdiA
Authors:Wang, J, Yashiro, Y, Tomita, K.
Deposit date:2021-10-08
Release date:2022-03-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.413 Å)
Cite:Mechanistic insights into tRNA cleavage by a contact-dependent growth inhibitor protein and translation factors.
Nucleic Acids Res., 50, 2022
3J5Y
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BU of 3j5y by Molmil
Structure of the mammalian ribosomal pre-termination complex associated with eRF1-eRF3-GDPNP
Descriptor: 5'-R(*AP*UP*UP*GP*UP*AP*AP*AP*AP*A)-3', Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, Eukaryotic peptide chain release factor subunit 1, ...
Authors:des Georges, A, Hashem, Y, Unbehaun, A, Grassucci, R.A, Taylor, D, Hellen, C.U.T, Pestova, T.V, Frank, J.
Deposit date:2013-11-21
Release date:2013-12-25
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (9.7 Å)
Cite:Structure of the mammalian ribosomal pre-termination complex associated with eRF1*eRF3*GDPNP.
Nucleic Acids Res., 42, 2014
5IZM
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BU of 5izm by Molmil
The crystal structure of human eEFSec in complex with GDPNP
Descriptor: MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Selenocysteine-specific elongation factor
Authors:Dobosz-Bartoszek, M, Otwinowski, Z, Simonovic, M.
Deposit date:2016-03-25
Release date:2016-10-12
Last modified:2019-11-27
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Crystal structures of the human elongation factor eEFSec suggest a non-canonical mechanism for selenocysteine incorporation.
Nat Commun, 7, 2016
3JCE
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BU of 3jce by Molmil
Structure of Escherichia coli EF4 in pretranslocational ribosomes (Pre EF4)
Descriptor: 16S ribosomal RNA, 23 ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Zhang, D, Yan, K, Liu, G, Song, G, Luo, J, Shi, Y, Cheng, E, Wu, S, Jiang, T, Low, J, Gao, N, Qin, Y.
Deposit date:2015-12-01
Release date:2016-01-13
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:EF4 disengages the peptidyl-tRNA CCA end and facilitates back-translocation on the 70S ribosome
Nat. Struct. Mol. Biol., 23, 2016
5IZK
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BU of 5izk by Molmil
The crystal structure of human eEFSec in complex with GDP
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Selenocysteine-specific elongation factor
Authors:Dobosz-Bartoszek, M, Simonovic, M.
Deposit date:2016-03-25
Release date:2016-10-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Crystal structures of the human elongation factor eEFSec suggest a non-canonical mechanism for selenocysteine incorporation.
Nat Commun, 7, 2016

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數據於2024-08-07公開中

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