4EZP
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4F01
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4EZT
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4EZR
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4EZW
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4H5V
| HSC70 NBD with Mg | Descriptor: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Stec, B. | Deposit date: | 2012-09-18 | Release date: | 2014-03-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | New crystal structures of HSC-70 ATP binding domain confirm the role of individual binding pockets and suggest a new method of inhibition. Biochimie, 108, 2015
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4FL9
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4H5W
| HSC70 NBD with betaine | Descriptor: | ACETATE ION, Heat shock cognate 71 kDa protein, MAGNESIUM ION, ... | Authors: | Stec, B. | Deposit date: | 2012-09-19 | Release date: | 2014-03-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | New crystal structures of HSC-70 ATP binding domain confirm the role of individual binding pockets and suggest a new method of inhibition. Biochimie, 108, 2015
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4EZS
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4EZY
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4HY9
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4EZN
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4EZX
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4HYB
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4H5T
| HSC70 NBD with ADP and Mg | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Heat shock cognate 71 kDa protein, MAGNESIUM ION, ... | Authors: | Stec, B. | Deposit date: | 2012-09-18 | Release date: | 2014-03-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | New crystal structures of HSC-70 ATP binding domain confirm the role of individual binding pockets and suggest a new method of inhibition. Biochimie, 108, 2015
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4H5N
| HSC70 NBD with PO4, Na, Cl | Descriptor: | CHLORIDE ION, GLYCEROL, Heat shock cognate 71 kDa protein, ... | Authors: | Stec, B. | Deposit date: | 2012-09-18 | Release date: | 2014-03-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | New crystal structures of HSC-70 ATP binding domain confirm the role of individual binding pockets and suggest a new method of inhibition. Biochimie, 108, 2015
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4IO8
| Crystal structure of human HSP70 complexed with 4-{(2R,3S,4R)-5-[(R)-6-Amino-8-(3,4-dichloro-benzylamino)-purin-9-yl]-3,4-dihydroxy-tetrahydro-furan-2-ylmethoxymethyl}-benzonitrile | Descriptor: | 4-[[(2R,3S,4R,5R)-5-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-oxolan-2-yl]methoxymethyl]benzonitrile, Heat shock 70kDa protein 1A variant | Authors: | Musil, D, Scholz, S. | Deposit date: | 2013-01-07 | Release date: | 2013-12-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | Functional analysis of hsp70 inhibitors. Plos One, 8, 2013
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4GNI
| Structure of the Ssz1 ATPase bound to ATP and Magnesium | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Putative heat shock protein | Authors: | Bange, G, Sinning, I. | Deposit date: | 2012-08-17 | Release date: | 2012-12-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.796 Å) | Cite: | Structural characterization of a eukaryotic chaperone-the ribosome-associated complex. Nat.Struct.Mol.Biol., 20, 2013
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4H5R
| HSC70 NBD with Na, Cl and glycerol | Descriptor: | CHLORIDE ION, GLYCEROL, Heat shock cognate 71 kDa protein, ... | Authors: | Stec, B. | Deposit date: | 2012-09-18 | Release date: | 2014-03-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | New crystal structures of HSC-70 ATP binding domain confirm the role of individual binding pockets and suggest a new method of inhibition. Biochimie, 108, 2015
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4EZO
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4EZZ
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4EZQ
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4FSV
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6ZMD
| Crystal structure of HYPE covalently tethered to BiP bound to AMP-PNP | Descriptor: | Endoplasmic reticulum chaperone BiP, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Fauser, J, Gulen, B, Pett, C, Hedberg, C, Itzen, A, Pogenberg, V. | Deposit date: | 2020-07-02 | Release date: | 2021-04-14 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | Specificity of AMPylation of the human chaperone BiP is mediated by TPR motifs of FICD. Nat Commun, 12, 2021
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4E81
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