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3LV3
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BU of 3lv3 by Molmil
Crystal structure of HLA-B*2705 complexed with a peptide derived from the human voltage-dependent calcium channel alpha1 subunit (residues 513-521)
Descriptor: 9-meric peptide from Voltage-dependent L-type calcium channel subunit alpha-1D, Beta-2-microglobulin, GLYCEROL, ...
Authors:Loll, B, Rueckert, C, Saenger, W, Uchanska-Ziegler, B, Ziegler, A.
Deposit date:2010-02-19
Release date:2010-11-24
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Loss of recognition by cross-reactive T cells and its relation to a C-terminus-induced conformational reorientation of an HLA-B*2705-bound peptide.
Protein Sci., 20, 2011
4NNY
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BU of 4nny by Molmil
Crystal structure of non-phosphorylated form of PKD2 phosphopeptide bound to HLA-A2
Descriptor: Beta-2-microglobulin, CADMIUM ION, GLYCEROL, ...
Authors:Mohammed, F, Stones, D.H, Willcox, B.E.
Deposit date:2013-11-19
Release date:2014-11-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status.
Oncotarget, 8, 2017
4NO5
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BU of 4no5 by Molmil
Crystal structure of non-phosphorylated form of AMPD2 phosphopeptide bound to HLA-A2
Descriptor: 1,2-ETHANEDIOL, AMP deaminase 2, Beta-2-microglobulin, ...
Authors:Mohammed, F, Stones, D.H, Willcox, B.E.
Deposit date:2013-11-19
Release date:2014-12-24
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status.
Oncotarget, 8, 2017
1T1X
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BU of 1t1x by Molmil
Structural basis for degenerate recognition of HIV peptide variants by cytotoxic lymphocyte, variant SL9-4L
Descriptor: Beta-2-microglobulin, GAG PEPTIDE, HLA class I histocompatibility antigen, ...
Authors:Martinez-Hackert, E, Anikeeva, N, Kalams, S.A, Walker, B.D, Hendrickson, W.A, Sykulev, Y.
Deposit date:2004-04-19
Release date:2005-09-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis for Degenerate Recognition of Natural HIV Peptide Variants by Cytotoxic Lymphocytes.
J.Biol.Chem., 281, 2006
3LKP
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BU of 3lkp by Molmil
Crystal Structure of HLA B*3501 in complex with influenza NP418 epitope from 1972 strain
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ...
Authors:Gras, S, Kedzierski, L, Valkenburg, S.A, Liu, Y.C, Denholm, J, Richards, M, Rimmelzwaan, G.F, Doherty, P.C, Turner, S.J, Rossjohn, J, Kedzierska, K.
Deposit date:2010-01-27
Release date:2010-07-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Cross-reactive CD8+ T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses.
Proc.Natl.Acad.Sci.USA, 107, 2010
3LOW
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BU of 3low by Molmil
Crystal structure of Beta 2 Microglobulin domain-swapped dimer
Descriptor: Beta-2-microglobulin, GLYCEROL
Authors:Liu, C, Eisenberg, D.
Deposit date:2010-02-04
Release date:2010-12-08
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Beta2-microglobulin forms three-dimensional domain-swapped amyloid fibrils with disulfide linkages.
Nat.Struct.Mol.Biol., 18, 2011
4NO2
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BU of 4no2 by Molmil
Crystal structure of RQA_V phosphopeptide bound to HLA-A2
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Mohammed, F, Stones, D.H, Willcox, B.E.
Deposit date:2013-11-19
Release date:2014-11-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status.
Oncotarget, 8, 2017
4NT6
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BU of 4nt6 by Molmil
HLA-C*0801 Crystal Structure
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, Cw-8 alpha chain, ...
Authors:Liu, J.X, Toh, X.Y, Ren, E.C.
Deposit date:2013-12-01
Release date:2014-07-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:The immunodominant influenza A virus M158-66 cytotoxic T lymphocyte epitope exhibits degenerate class I major histocompatibility complex restriction in humans.
J.Virol., 88, 2014
4NNX
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BU of 4nnx by Molmil
Crystal structure of PKD2 phosphopeptide bound to HLA-A2
Descriptor: Beta-2-microglobulin, CADMIUM ION, GLYCEROL, ...
Authors:Mohammed, F, Stones, D.H, Willcox, B.E.
Deposit date:2013-11-19
Release date:2014-11-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.104 Å)
Cite:The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status.
Oncotarget, 8, 2017
3TID
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BU of 3tid by Molmil
Crystal structure of the LCMV derived peptide GP34 in complex with the murine mhc class I H-2 Kb
Descriptor: ACETATE ION, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
Authors:Nguyen, T.T, Shen, Z.T, Stern, L.J.
Deposit date:2011-08-20
Release date:2012-08-22
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Disparate epitopes mediating protective heterologous immunity to unrelated viruses share peptide-MHC structural features recognized by cross-reactive T cells.
J.Immunol., 191, 2013
4NQD
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BU of 4nqd by Molmil
Crystal structure of TCR-MR1 ternary complex and non-covalently bound 5-(2-oxopropylideneamino)-6-D-ribitylaminouracil
Descriptor: 1-deoxy-1-({2,6-dioxo-5-[(E)-(2-oxopropylidene)amino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, GLYCEROL, ...
Authors:Birkinshaw, R.W, Rossjohn, J.
Deposit date:2013-11-25
Release date:2014-04-16
Last modified:2014-11-19
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:T-cell activation by transitory neo-antigens derived from distinct microbial pathways.
Nature, 509, 2014
4NQV
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BU of 4nqv by Molmil
Crystal Structure of HLA A*0101 in complex with NP44, an 9-mer influenza epitope
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-1 alpha chain, ...
Authors:Rossjohn, J, Gras, S.
Deposit date:2013-11-25
Release date:2013-12-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Preexisting CD8+ T-cell immunity to the H7N9 influenza A virus varies across ethnicities.
Proc.Natl.Acad.Sci.USA, 111, 2014
1TVB
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BU of 1tvb by Molmil
Crystal structure of Melanoma Antigen gp100(209-217) Bound to Human Class I MHC HLA-A2
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2004-06-29
Release date:2005-04-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Increased Immunogenicity of an Anchor-Modified Tumor-Associated Antigen Is Due to the Enhanced Stability of the Peptide/MHC Complex: Implications for Vaccine Design
J.Immunol., 174, 2005
1TVH
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BU of 1tvh by Molmil
Crystal structure of Modified Melanoma Antigen gp100(209-T2M) Bound to Human Class I MHC HLA-A2
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2004-06-29
Release date:2005-04-19
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:Increased Immunogenicity of an Anchor-Modified Tumor-Associated Antigen Is Due to the Enhanced Stability of the Peptide/MHC Complex: Implications for Vaccine Design
J.Immunol., 174, 2005
3QEQ
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BU of 3qeq by Molmil
The complex between TCR DMF4 and human Class I MHC HLA-A2 with the bound MART-1(27-35) nonameric peptide
Descriptor: Beta-2-microglobulin, DMF4 alpha chain, DMF4 beta chain, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2011-01-20
Release date:2011-07-06
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:TCRs Used in Cancer Gene Therapy Cross-React with MART-1/Melan-A Tumor Antigens via Distinct Mechanisms.
J.Immunol., 187, 2011
3QFJ
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BU of 3qfj by Molmil
The complex between TCR A6 and human Class I MHC HLA-A2 with the modified TAX (Y5F) peptide
Descriptor: A6 alpha chain, A6 beta chain, Beta-2-microglobulin, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2011-01-21
Release date:2012-01-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Disparate degrees of hypervariable loop flexibility control T-cell receptor cross-reactivity, specificity, and binding mechanism.
J.Mol.Biol., 414, 2011
4O2C
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BU of 4o2c by Molmil
An Nt-acetylated peptide complexed with HLA-B*3901
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-39 alpha chain, ...
Authors:Sun, M, Liu, J, Qi, J, Tefsen, B, Shi, Y, Yan, J, Gao, G.F.
Deposit date:2013-12-17
Release date:2014-07-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:N alpha-terminal acetylation for T cell recognition: molecular basis of MHC class I-restricted n alpha-acetylpeptide presentation
J.Immunol., 192, 2014
3QDM
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BU of 3qdm by Molmil
The complex between TCR DMF4 and human Class I MHC HLA-A2 with the bound MART-1(26-35)(A27L) decameric peptide
Descriptor: Beta-2-microglobulin, DMF4 alpha chain, DMF4 beta chain, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2011-01-18
Release date:2011-07-06
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:TCRs Used in Cancer Gene Therapy Cross-React with MART-1/Melan-A Tumor Antigens via Distinct Mechanisms.
J.Immunol., 187, 2011
3PWJ
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BU of 3pwj by Molmil
Human Class I MHC HLA-A2 in complex with the HuD (G2L,I9V) peptide variant
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2010-12-08
Release date:2011-03-09
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Conformational Melding Permits a Conserved Binding Geometry in TCR Recognition of Foreign and Self Molecular Mimics.
J.Immunol., 186, 2011
1W0V
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BU of 1w0v by Molmil
Crystal Structure Of HLA-B*2705 Complexed With the self-Peptide TIS from EGF-response factor 1
Descriptor: BETA-2-MICROGLOBULIN, BUTYRATE RESPONSE FACTOR 2, GLYCEROL, ...
Authors:Hulsmeyer, M, Fiorillo, M.T, Bettosini, F, Sorrentino, R, Saenger, W, Ziegler, A, Uchanska-Ziegler, B.
Deposit date:2004-06-14
Release date:2005-03-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Thermodynamic and Structural Equivalence of Two Hla-B27 Subtypes Complexed with a Self-Peptide
J.Mol.Biol., 346, 2005
3TLR
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BU of 3tlr by Molmil
Crystal Structure of the tetrameric Beta-2 microglobulin DIMC20 mutant
Descriptor: Beta-2-microglobulin, CADMIUM ION, SODIUM ION
Authors:Colombo, M, Ricagno, S, Bolognesi, M.
Deposit date:2011-08-30
Release date:2012-09-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:A recurrent D-strand association interface is observed in beta-2 microglobulin oligomers.
Febs J., 279, 2012
3TO2
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BU of 3to2 by Molmil
Structure of HLA-A*0201 complexed with peptide Md3-C9 derived from a clustering region of restricted cytotoxic T lymphocyte epitope from SARS-CoV M protein
Descriptor: Beta-2-microglobulin, MHC class I antigen, Md3-C9 peptide derived from Membrane glycoprotein
Authors:Liu, J, Qi, J, Gao, F, Yan, J, Gao, G.F.
Deposit date:2011-09-03
Release date:2012-08-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Functional and Structural Definition of a Clustering Region of HLA-A2-restricted Cytotoxic T Lymphocyte Epitopes
Sci.Technology Rev., 29, 2011
1VGK
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BU of 1vgk by Molmil
The crystal structure of class I Major histocompatibility complex, H-2Kd at 2.0 A resolution
Descriptor: Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-D alpha chain, ...
Authors:Zhou, M, Xu, Y, Liu, Y, Gao, G.F, Tien, P, Rao, Z.
Deposit date:2004-04-27
Release date:2005-06-28
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:The crystal structure of class I major histocompatibility complex, H-2Kd at 2.0 A resolution
To be Published
1HLA
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BU of 1hla by Molmil
STRUCTURE OF THE HUMAN CLASS I HISTOCOMPATIBILITY ANTIGEN, HLA-A2
Descriptor: BETA 2-MICROGLOBULIN, CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A2) (ALPHA CHAIN)
Authors:Bjorkman, P.J, Saper, M.A, Samraoui, B, Bennett, W.S, Strominger, J.L, Wiley, D.C.
Deposit date:1987-10-15
Release date:1988-01-16
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of the human class I histocompatibility antigen, HLA-A2.
Nature, 329, 1987
1HSB
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BU of 1hsb by Molmil
DIFFERENT LENGTH PEPTIDES BIND TO HLA-AW68 SIMILARLY AT THEIR ENDS BUT BULGE OUT IN THE MIDDLE
Descriptor: ALANINE, ARGININE, BOUND PEPTIDE FRAGMENT, ...
Authors:Guo, H.-C, Strominger, J.L, Wiley, D.C.
Deposit date:1993-03-30
Release date:1993-10-31
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middle.
Nature, 360, 1992

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數據於2024-07-10公開中

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