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4PRI
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BU of 4pri by Molmil
Crystal structure of TK3 TCR-HLA-B*35:08-HPVG complex
Descriptor: Beta-2-microglobulin, CHLORIDE ION, Epstein-Barr nuclear antigen 1, ...
Authors:Yu Chih, L, Rossjohn, J, Gras, S.
Deposit date:2014-03-05
Release date:2014-04-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A Molecular Basis for the Interplay between T Cells, Viral Mutants, and Human Leukocyte Antigen Micropolymorphism.
J.Biol.Chem., 289, 2014
3TZV
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BU of 3tzv by Molmil
Crystal structure of an iNKT TCR in complex with CD1d-lysophosphatidylcholine
Descriptor: (4R,7R,18E)-4,7-dihydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphaheptacos-18-en-1-aminium 4-oxide, Antigen-presenting glycoprotein CD1d, Beta-2-microglobulin, ...
Authors:Lopez-Sagaseta, J, Adams, E.J.
Deposit date:2011-09-27
Release date:2012-04-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.056 Å)
Cite:Lysophospholipid presentation by CD1d and recognition by a human Natural Killer T-cell receptor.
Embo J., 31, 2012
4PJ7
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BU of 4pj7 by Molmil
Structure of human MR1-5-OP-RU in complex with human MAIT TRBV6-4 TCR
Descriptor: 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, ...
Authors:Birkinshaw, R.W, Rossjohn, J.
Deposit date:2014-05-12
Release date:2014-07-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells.
J.Exp.Med., 211, 2014
6D29
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BU of 6d29 by Molmil
HLA-B*57:01 presenting TSMSFVPRPW
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-57 alpha chain, ...
Authors:Vivian, J.P, Rossjohn, J.
Deposit date:2018-04-13
Release date:2018-10-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands.
Sci Immunol, 3, 2018
3TM6
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BU of 3tm6 by Molmil
Crystal structure of the beta-2 microglobulin DIMC50 disulphide-linked homodimer mutant
Descriptor: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION
Authors:Colombo, M, Ricagno, S, Bolognesi, M.
Deposit date:2011-08-31
Release date:2012-09-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A recurrent D-strand association interface is observed in beta-2 microglobulin oligomers.
Febs J., 279, 2012
3OX8
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BU of 3ox8 by Molmil
Crystal Structure of HLA A*02:03 Bound to HBV Core 18-27
Descriptor: 10mer peptide from Pre-core-protein, Beta-2-microglobulin, MHC class I antigen
Authors:Liu, J, Chen, Y, Lai, L, Ren, E.
Deposit date:2010-09-21
Release date:2011-05-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Structural insights into the binding of hepatitis B virus core peptide to HLA-A2 alleles: Towards designing better vaccines.
Eur.J.Immunol., 41, 2011
4PRA
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BU of 4pra by Molmil
Crystal structure of a HLA-B*35:01-HPVG-Q5
Descriptor: Beta-2-microglobulin, Epstein-Barr nuclear antigen 1, MHC class I antigen
Authors:Yu Chih, L, Rossjohn, J, Gras, S.
Deposit date:2014-03-05
Release date:2014-04-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A Molecular Basis for the Interplay between T Cells, Viral Mutants, and Human Leukocyte Antigen Micropolymorphism.
J.Biol.Chem., 289, 2014
3U0P
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BU of 3u0p by Molmil
Crystal structure of human CD1d-lysophosphatidylcholine
Descriptor: (4R,7R,18E)-4,7-dihydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphaheptacos-18-en-1-aminium 4-oxide, Antigen-presenting glycoprotein CD1d, Beta-2-microglobulin, ...
Authors:Lopez-Sagaseta, J, Sibener, L.V, Adams, E.J.
Deposit date:2011-09-28
Release date:2012-04-25
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Lysophospholipid presentation by CD1d and recognition by a human Natural Killer T-cell receptor.
Embo J., 31, 2012
4PRH
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BU of 4prh by Molmil
Crystal structure of TK3 TCR-HLA-B*35:08-HPVG-D5 complex
Descriptor: Beta-2-microglobulin, Epstein-Barr nuclear antigen 1, MHC class I antigen, ...
Authors:Yu Chih, L, Rossjohn, J, Gras, S.
Deposit date:2014-03-05
Release date:2014-04-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A Molecular Basis for the Interplay between T Cells, Viral Mutants, and Human Leukocyte Antigen Micropolymorphism.
J.Biol.Chem., 289, 2014
3OXS
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BU of 3oxs by Molmil
Crystal Structure of HLA A*02:07 Bound to HBV Core 18-27
Descriptor: 10mer peptide from Pre-core-protein, Beta-2-microglobulin, MHC class I antigen
Authors:Liu, J, Chen, Y, Lai, L, Ren, E.
Deposit date:2010-09-22
Release date:2011-05-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural insights into the binding of hepatitis B virus core peptide to HLA-A2 alleles: Towards designing better vaccines.
Eur.J.Immunol., 41, 2011
4QOK
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BU of 4qok by Molmil
Structural basis for ineffective T-cell responses to MHC anchor residue improved heteroclitic peptides
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Rizkallah, P.J, Cole, D.K, Madura, F, Sewell, A.K.
Deposit date:2014-06-20
Release date:2014-12-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for ineffective T-cell responses to MHC anchor residue-improved "heteroclitic" peptides.
Eur.J.Immunol., 45, 2015
1S8D
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BU of 1s8d by Molmil
Structural basis for degenerate recognition of HIV peptide variants by cytotoxic lymphocyte, variant SL9-3A
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ...
Authors:Martinez-Hackert, E, Anikeeva, N, Kalams, S.A, Walker, B.D, Hendrickson, W.A, Sykulev, Y.
Deposit date:2004-02-02
Release date:2005-09-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis for Degenerate Recognition of Natural HIV Peptide Variants by Cytotoxic Lymphocytes.
J.Biol.Chem., 281, 2006
4KDT
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BU of 4kdt by Molmil
Structure of an early native-like intermediate of beta2-microglobulin amyloidosis
Descriptor: Beta-2-microglobulin, GLYCEROL, Nanobody24, ...
Authors:Vanderhaegen, S, Fislage, M, Pardon, E, Versees, W, Steyaert, J.
Deposit date:2013-04-25
Release date:2013-08-28
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of an early native-like intermediate of beta 2-microglobulin amyloidogenesis.
Protein Sci., 22, 2013
3LKN
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BU of 3lkn by Molmil
Crystal Structure of HLA B*3501 in complex with influenza NP418 epitope from 1918 strain
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ...
Authors:Gras, S, Kedzierski, L, Valkenburg, S.A, Liu, Y.C, Denholm, J, Richards, M, Rimmelzwaan, G.F, Doherty, P.C, Turner, S.J, Rossjohn, J, Kedzierska, K.
Deposit date:2010-01-27
Release date:2010-07-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Cross-reactive CD8+ T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses.
Proc.Natl.Acad.Sci.USA, 107, 2010
3LN4
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BU of 3ln4 by Molmil
Crystal structure of HLA-B*4103 in complex with a 16mer self-peptide derived from heterogeneous nuclear ribonucleoproteins C1/C2
Descriptor: 16-mer peptide from Heterogeneous nuclear ribonucleoproteins C1/C2, ACETATE ION, Beta-2-microglobulin, ...
Authors:Theodossis, A, Gras, S, Rossjohn, J.
Deposit date:2010-02-01
Release date:2010-10-20
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.296 Å)
Cite:The impact of human leukocyte antigen (HLA) micropolymorphism on ligand specificity within the HLA-B*41 allotypic family
Haematologica, 96, 2011
4RMU
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BU of 4rmu by Molmil
Crystal structure of the D76E Beta-2 Microglobulin mutant
Descriptor: Beta-2-microglobulin, TRIETHYLENE GLYCOL
Authors:de Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2014-10-22
Release date:2015-11-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.
Nat Commun, 9, 2018
4NQE
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BU of 4nqe by Molmil
Crystal structure of TCR-MR1 ternary complex bound to 5-(2-oxoethylideneamino)-6-D-ribitylaminouracil
Descriptor: 1-deoxy-1-({2,6-dioxo-5-[(E)-(2-oxoethylidene)amino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, ...
Authors:Birkinshaw, R.W, Rossjohn, J.
Deposit date:2013-11-25
Release date:2014-04-16
Last modified:2020-02-19
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:T-cell activation by transitory neo-antigens derived from distinct microbial pathways.
Nature, 509, 2014
4NQX
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BU of 4nqx by Molmil
Crystal Structure of HLA A*0101 in complex with NP44-S7N, an 9-mer influenza epitope
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-1 alpha chain, ...
Authors:Rossjohn, J, Gras, S.
Deposit date:2013-11-26
Release date:2013-12-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Preexisting CD8+ T-cell immunity to the H7N9 influenza A virus varies across ethnicities.
Proc.Natl.Acad.Sci.USA, 111, 2014
3RL2
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BU of 3rl2 by Molmil
HIV Nef derived peptide Nef73 complexed to HLA-A*0301
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-3 alpha chain, ...
Authors:Zhang, S, Liu, J, Cheng, H, Tan, S, Qi, J, Yan, J, Gao, G.F.
Deposit date:2011-04-19
Release date:2012-02-29
Method:X-RAY DIFFRACTION (2.386 Å)
Cite:Structural basis of cross-allele presentation by HLA-A*0301 and HLA-A*1101 revealed by two HIV-derived peptide complexes
Mol.Immunol., 49, 2011
3LKO
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BU of 3lko by Molmil
Crystal Structure of HLA B*3501 in complex with influenza NP418 epitope from 1934 strain
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ...
Authors:Gras, S, Kedzierski, L, Valkenburg, S.A, Liu, Y.C, Denholm, J, Richards, M, Rimmelzwaan, G.F, Doherty, P.C, Turner, S.J, Rossjohn, J, Kedzierska, K.
Deposit date:2010-01-27
Release date:2010-07-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Cross-reactive CD8+ T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses.
Proc.Natl.Acad.Sci.USA, 107, 2010
4RMV
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BU of 4rmv by Molmil
Crystal structure of the D76H Beta-2 Microglobulin mutant
Descriptor: ACETATE ION, Beta-2-microglobulin, TRIETHYLENE GLYCOL
Authors:de Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2014-10-22
Release date:2015-11-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.463 Å)
Cite:Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.
Nat Commun, 9, 2018
1T22
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BU of 1t22 by Molmil
Structural basis for degenerate recognition of HIV peptide variants by cytotoxic lymphocyte, variant SL9, orthorhombic crystal
Descriptor: Beta-2-microglobulin, GAG PEPTIDE, HLA class I histocompatibility antigen, ...
Authors:Martinez-Hackert, E, Anikeeva, N, Kalams, S.A, Walker, B.D, Hendrickson, W.A, Sykulev, Y.
Deposit date:2004-04-19
Release date:2005-09-06
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis for Degenerate Recognition of Natural HIV Peptide Variants by Cytotoxic Lymphocytes.
J.Biol.Chem., 281, 2006
4U1M
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BU of 4u1m by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2014-07-15
Release date:2015-04-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.18 Å)
Cite:A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
3REW
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BU of 3rew by Molmil
Crystal structure of an lmp2a-derived peptide bound to human class i mhc hla-a2
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, CHLORIDE ION, ...
Authors:Wood, A, Mohammed, F, Salim, M, Tranter, A, Rickinson, A.B, Moss, P.A.H, Stauss, H.J, Steven, N.M, Willcox, B.E.
Deposit date:2011-04-05
Release date:2012-01-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and energetic evidence for highly peptide-specific tumor antigen targeting via allo-MHC restriction.
Proc.Natl.Acad.Sci.USA, 108, 2011
4U1I
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BU of 4u1i by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, GAG protein, ...
Authors:Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
Deposit date:2014-07-15
Release date:2015-04-08
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015

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數據於2024-07-10公開中

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