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4HNA
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BU of 4hna by Molmil
Kinesin motor domain in the ADP-MG-ALFX state in complex with tubulin and a DARPIN
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN) D2, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Gigant, B, Knossow, M.
Deposit date:2012-10-19
Release date:2013-06-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Structure of a kinesin-tubulin complex and implications for kinesin motility.
Nat.Struct.Mol.Biol., 20, 2013
3J6H
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BU of 3j6h by Molmil
Nucleotide-free Kinesin motor domain complexed with GMPCPP-microtubule
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, Kinesin heavy chain isoform 5C, MAGNESIUM ION, ...
Authors:Morikawa, M, Yajima, H, Nitta, R, Inoue, S, Ogura, T, Sato, C, Hirokawa, N.
Deposit date:2014-02-21
Release date:2015-04-01
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (8.1 Å)
Cite:X-ray and Cryo-EM structures reveal mutual conformational changes of Kinesin and GTP-state microtubules upon binding
Embo J., 2015
8IXB
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BU of 8ixb by Molmil
GMPCPP-Alpha1A/Beta2A-microtubule decorated with kinesin seam region
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ...
Authors:Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y.
Deposit date:2023-03-31
Release date:2023-08-16
Last modified:2023-10-25
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules.
Acta Biochim.Biophys.Sin., 55, 2023
8IXG
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BU of 8ixg by Molmil
GMPCPP-Alpha4A/Beta2A-microtubule decorated with kinesin seam region
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ...
Authors:Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y.
Deposit date:2023-03-31
Release date:2023-08-16
Last modified:2023-10-25
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules.
Acta Biochim.Biophys.Sin., 55, 2023
8IXE
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BU of 8ixe by Molmil
GMPCPP-Alpha1C/Beta2A-microtubule decorated with kinesin seam region
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ...
Authors:Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y.
Deposit date:2023-03-31
Release date:2023-08-16
Last modified:2023-10-25
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules.
Acta Biochim.Biophys.Sin., 55, 2023
8IXA
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BU of 8ixa by Molmil
GMPCPP-Alpha1A/Beta2A-microtubule decorated with kinesin non-seam region
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ...
Authors:Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y.
Deposit date:2023-03-31
Release date:2023-08-16
Last modified:2023-10-25
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules.
Acta Biochim.Biophys.Sin., 55, 2023
8IXD
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BU of 8ixd by Molmil
GMPCPP-Alpha1C/Beta2A-microtubule decorated with kinesin non-seam region
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ...
Authors:Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y.
Deposit date:2023-03-31
Release date:2023-08-16
Last modified:2023-10-25
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules.
Acta Biochim.Biophys.Sin., 55, 2023
8IXF
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BU of 8ixf by Molmil
GMPCPP-Alpha4A/Beta2A-microtubule decorated with kinesin non-seam region
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ...
Authors:Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y.
Deposit date:2023-03-31
Release date:2023-08-16
Last modified:2023-10-25
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules.
Acta Biochim.Biophys.Sin., 55, 2023
6TIW
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BU of 6tiw by Molmil
Human kinesin-5 motor domain in the GSK state bound to microtubules (Conformation 2)
Descriptor: 6-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1~{H}-quinolin-2-one, Kinesin-like protein KIF11, MAGNESIUM ION, ...
Authors:Pena, A, Sweeney, A, Cook, A.D, Moores, C.A, Topf, M.
Deposit date:2019-11-22
Release date:2020-03-04
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy.
Structure, 28, 2020
2P4N
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BU of 2p4n by Molmil
Human Monomeric Kinesin (1BG2) and Bovine Tubulin (1JFF) Docked into the 9-Angstrom Cryo-EM Map of Nucleotide-Free Kinesin Complexed to the Microtubule
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Sindelar, C.V, Downing, K.H.
Deposit date:2007-03-12
Release date:2008-07-08
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (9 Å)
Cite:The beginning of kinesin's force-generating cycle visualized at 9-A resolution.
J.Cell Biol., 177, 2007
6TA4
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BU of 6ta4 by Molmil
Human kinesin-5 motor domain in the AMPPNP state bound to microtubules
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF11, MAGNESIUM ION, ...
Authors:Pena, A.P, Sweeney, A, Cook, A.D, Moores, C.A, Topf, M.
Deposit date:2019-10-29
Release date:2020-03-04
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy.
Structure, 28, 2020
5HNZ
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BU of 5hnz by Molmil
Structural basis of backwards motion in kinesin-14: plus-end directed nKn669 in the nucleotide-free state
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Shigematsu, H, Yokoyama, T, Kikkawa, M, Shirouzu, M, Nitta, R.
Deposit date:2016-01-19
Release date:2016-08-10
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Structural Basis of Backwards Motion in Kinesin-1-Kinesin-14 Chimera: Implication for Kinesin-14 Motility
Structure, 24, 2016
5HNW
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BU of 5hnw by Molmil
Structural basis of backwards motion in kinesin-14: minus-end directed nKn664 in the AMPPNP state
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Shigematsu, H, Yokoyama, T, Kikkawa, M, Shirouzu, M, Nitta, R.
Deposit date:2016-01-19
Release date:2016-08-10
Last modified:2018-07-25
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Structural Basis of Backwards Motion in Kinesin-1-Kinesin-14 Chimera: Implication for Kinesin-14 Motility
Structure, 24, 2016
5HNX
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BU of 5hnx by Molmil
Structural basis of backwards motion in kinesin-14: minus-end directed nKn664 in the nucleotide-free state
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Shigematsu, H, Yokoyama, T, Kikkawa, M, Shirouzu, M, Nitta, R.
Deposit date:2016-01-19
Release date:2016-08-10
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Structural Basis of Backwards Motion in Kinesin-1-Kinesin-14 Chimera: Implication for Kinesin-14 Motility
Structure, 24, 2016
7NBA
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BU of 7nba by Molmil
Plasmodium falciparum kinesin-5 motor domain bound to AMPPNP, complexed with 14 protofilament microtubule.
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, Kinesin motor domain-containing protein,Kinesin motor domain-containing protein, MAGNESIUM ION, ...
Authors:Cook, A.D, Roberts, A, Atherton, J, Tewari, R, Topf, M, Moores, C.A.
Deposit date:2021-01-25
Release date:2021-10-13
Last modified:2021-10-27
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cryo-EM structure of a microtubule-bound parasite kinesin motor and implications for its mechanism and inhibition.
J.Biol.Chem., 297, 2021
7NB8
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BU of 7nb8 by Molmil
Plasmodium falciparum kinesin-5 motor domain without nucleotide, complexed with 14 protofilament microtubule.
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, Kinesin-5, MAGNESIUM ION, ...
Authors:Cook, A.D, Roberts, A, Atherton, J, Tewari, R, Topf, M, Moores, C.A.
Deposit date:2021-01-25
Release date:2021-10-13
Last modified:2021-10-27
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Cryo-EM structure of a microtubule-bound parasite kinesin motor and implications for its mechanism and inhibition.
J.Biol.Chem., 297, 2021
7N61
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BU of 7n61 by Molmil
structure of C2 projections and MIPs
Descriptor: ADENOSINE-5'-DIPHOSPHATE, FAP147, FAP178, ...
Authors:Han, L, Zhang, K.
Deposit date:2021-06-07
Release date:2022-05-18
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structure of an active central apparatus.
Nat.Struct.Mol.Biol., 29, 2022
5HNY
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BU of 5hny by Molmil
Structural basis of backwards motion in kinesin-14: plus-end directed nKn669 in the AMPPNP state
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Shigematsu, H, Yokoyama, T, Kikkawa, M, Shirouzu, M, Nitta, R.
Deposit date:2016-01-19
Release date:2016-08-10
Last modified:2016-11-02
Method:ELECTRON MICROSCOPY (6.3 Å)
Cite:Structural Basis of Backwards Motion in Kinesin-1-Kinesin-14 Chimera: Implication for Kinesin-14 Motility
Structure, 24, 2016
6VPP
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BU of 6vpp by Molmil
Cryo-EM structure of microtubule-bound KLP61F motor with tail domain in the nucleotide-free state
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein Klp61F, ...
Authors:Bodrug, T, Wilson-Kubalek, E.M, Nithianantham, S, Debs, G, Sindelar, C.V, Milligan, R, Al-Bassam, J.
Deposit date:2020-02-04
Release date:2020-02-19
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding.
Elife, 9, 2020
7LVQ
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BU of 7lvq by Molmil
KIF14[391-743] - AMP-PNP closed state class in complex with a microtubule
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF14, ...
Authors:Benoit, M.P.M.H, Asenjo, A.B, Paydar, M, Dhakal, S, Kwok, B, Sosa, H.
Deposit date:2021-02-26
Release date:2021-05-05
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of mechano-chemical coupling by the mitotic kinesin KIF14.
Nat Commun, 12, 2021
7LVR
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BU of 7lvr by Molmil
KIF14[391-743] - ADP-AlFx closed state class in complex with a microtubule
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Benoit, M.P.M.H, Asenjo, A.B, Paydar, M, Dhakal, S, Kwok, B, Sosa, H.
Deposit date:2021-02-26
Release date:2021-05-05
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of mechano-chemical coupling by the mitotic kinesin KIF14.
Nat Commun, 12, 2021
6VPO
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BU of 6vpo by Molmil
Cryo-EM structure of microtubule-bound KLP61F motor domain in the AMPPNP state
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein Klp61F, ...
Authors:Bodrug, T, Wilson-Kubalek, E.M, Nithianantham, S, Debs, G, Sindelar, C.V, Milligan, R, Al-Bassam, J.
Deposit date:2020-02-04
Release date:2020-02-19
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding.
Elife, 9, 2020
6TA3
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BU of 6ta3 by Molmil
Human kinesin-5 motor domain in the GSK-1 state bound to microtubules (Conformation 1)
Descriptor: 6-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1~{H}-quinolin-2-one, Kinesin-like protein KIF11, MAGNESIUM ION, ...
Authors:Pena, A, Sweeney, A, Cook, A.D, Moores, C.A, Topf, M.
Deposit date:2019-10-29
Release date:2020-04-22
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy.
Structure, 28, 2020
3DCO
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BU of 3dco by Molmil
Drosophila NOD (3DC4) and Bovine Tubulin (1JFF) Docked into the 11-Angstrom Cryo-EM Map of Nucleotide-Free NOD Complexed to the Microtubule
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Bovine Alpha Tubulin, Bovine Beta Tubulin, ...
Authors:Sindelar, C.V, Cochran, J.C, Kull, F.J.
Deposit date:2008-06-04
Release date:2009-02-10
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (11 Å)
Cite:ATPase cycle of the nonmotile kinesin NOD allows microtubule end tracking and drives chromosome movement.
Cell(Cambridge,Mass.), 136, 2009
7TR3
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BU of 7tr3 by Molmil
CaKip3[2-482] - AMP-PNP in complex with a dolastatin-10-stabilized tubulin ring
Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein, ...
Authors:Benoit, M.P.M.H, Asenjo, A.B, Hunter, B, Allingham, J.S, Sosa, H.
Deposit date:2022-01-27
Release date:2022-07-20
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Kinesin-8-specific loop-2 controls the dual activities of the motor domain according to tubulin protofilament shape.
Nat Commun, 13, 2022

221716

數據於2024-06-26公開中

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