PDB: 253 resultsInfo pagesStatus searchChemie searchBIRD

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6ZPI	Microtubule complexed with Kif15 motor domain. Symmetrised asymmetric unit Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF15, ... Authors: Atherton, J, Hummel, J.J.A, Olieric, N, Locke, J, Pena, A, Rosenfeld, S.S, Steinmetz, M.O, Hoogenraad, C.C, Moores, C.A. Deposit date: 2020-07-08 Release date: 2020-12-30 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: The mechanism of kinesin inhibition by kinesin-binding protein. Elife, 9, 2020
1IA0	KIF1A HEAD-MICROTUBULE COMPLEX STRUCTURE IN ATP-FORM Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-LIKE PROTEIN KIF1A, ... Authors: Kikkawa, M, Sablin, E.P, Okada, Y, Yajima, H, Fletterick, R.J, Hirokawa, N. Deposit date: 2001-03-22 Release date: 2002-03-22 Last modified: 2021-10-27 Method: ELECTRON MICROSCOPY (15 Å) Cite: Switch-based Mechanism of Kinesin Motors Nature, 411, 2001
6OJQ	Monomeric kinesin-1 motor domain in no-nucleotide state bound to GMPCPP-stabilized microtubule Descriptor: GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, MAGNESIUM ION, ... Authors: Cha, H.K, Debs, G. Deposit date: 2019-04-12 Release date: 2020-04-15 Last modified: 2024-03-20 Method: ELECTRON MICROSCOPY (3.67 Å) Cite: Structural Intermediates of the Dimeric Kinesin Stepping Cycle Revealed by Cryo-EM To Be Published
8IXF	GMPCPP-Alpha4A/Beta2A-microtubule decorated with kinesin non-seam region Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... Authors: Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y. Deposit date: 2023-03-31 Release date: 2023-08-16 Last modified: 2023-10-25 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules. Acta Biochim.Biophys.Sin., 55, 2023
8IXG	GMPCPP-Alpha4A/Beta2A-microtubule decorated with kinesin seam region Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... Authors: Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y. Deposit date: 2023-03-31 Release date: 2023-08-16 Last modified: 2023-10-25 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules. Acta Biochim.Biophys.Sin., 55, 2023
8IXE	GMPCPP-Alpha1C/Beta2A-microtubule decorated with kinesin seam region Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... Authors: Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y. Deposit date: 2023-03-31 Release date: 2023-08-16 Last modified: 2023-10-25 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules. Acta Biochim.Biophys.Sin., 55, 2023
8IXD	GMPCPP-Alpha1C/Beta2A-microtubule decorated with kinesin non-seam region Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... Authors: Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y. Deposit date: 2023-03-31 Release date: 2023-08-16 Last modified: 2023-10-25 Method: ELECTRON MICROSCOPY (4.4 Å) Cite: Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules. Acta Biochim.Biophys.Sin., 55, 2023
8IXB	GMPCPP-Alpha1A/Beta2A-microtubule decorated with kinesin seam region Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... Authors: Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y. Deposit date: 2023-03-31 Release date: 2023-08-16 Last modified: 2023-10-25 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules. Acta Biochim.Biophys.Sin., 55, 2023
6S8M	S. pombe microtubule decorated with Cut7 motor domain in the AMPPNP state Descriptor: 7,11-DIHYDROXY-8,8,10,12,16-PENTAMETHYL-3-[1-METHYL-2-(2-METHYL-THIAZOL-4-YL)VINYL]-4,17-DIOXABICYCLO[14.1.0]HEPTADECANE-5,9-DIONE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Moores, C.A, von Loeffelholz, O. Deposit date: 2019-07-10 Release date: 2019-08-21 Last modified: 2023-09-20 Method: ELECTRON MICROSCOPY (4.5 Å) Cite: Cryo-EM Structure (4.5- angstrom ) of Yeast Kinesin-5-Microtubule Complex Reveals a Distinct Binding Footprint and Mechanism of Drug Resistance. J.Mol.Biol., 431, 2019
6TIW	Human kinesin-5 motor domain in the GSK state bound to microtubules (Conformation 2) Descriptor: 6-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1~{H}-quinolin-2-one, Kinesin-like protein KIF11, MAGNESIUM ION, ... Authors: Pena, A, Sweeney, A, Cook, A.D, Moores, C.A, Topf, M. Deposit date: 2019-11-22 Release date: 2020-03-04 Last modified: 2024-05-15 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy. Structure, 28, 2020
6TA4	Human kinesin-5 motor domain in the AMPPNP state bound to microtubules Descriptor: GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF11, MAGNESIUM ION, ... Authors: Pena, A.P, Sweeney, A, Cook, A.D, Moores, C.A, Topf, M. Deposit date: 2019-10-29 Release date: 2020-03-04 Last modified: 2024-05-22 Method: ELECTRON MICROSCOPY (6.1 Å) Cite: Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy. Structure, 28, 2020
6TA3	Human kinesin-5 motor domain in the GSK-1 state bound to microtubules (Conformation 1) Descriptor: 6-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1~{H}-quinolin-2-one, Kinesin-like protein KIF11, MAGNESIUM ION, ... Authors: Pena, A, Sweeney, A, Cook, A.D, Moores, C.A, Topf, M. Deposit date: 2019-10-29 Release date: 2020-04-22 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy. Structure, 28, 2020
8IXA	GMPCPP-Alpha1A/Beta2A-microtubule decorated with kinesin non-seam region Descriptor: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... Authors: Zheng, W, Zhao, Q.Y, Diao, L, Bao, L, Cong, Y. Deposit date: 2023-03-31 Release date: 2023-08-16 Last modified: 2023-10-25 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: Cryo-EM of alpha-tubulin isotype-containing microtubules revealed a contracted structure of alpha 4A/ beta 2A microtubules. Acta Biochim.Biophys.Sin., 55, 2023
2P4N	Human Monomeric Kinesin (1BG2) and Bovine Tubulin (1JFF) Docked into the 9-Angstrom Cryo-EM Map of Nucleotide-Free Kinesin Complexed to the Microtubule Descriptor: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... Authors: Sindelar, C.V, Downing, K.H. Deposit date: 2007-03-12 Release date: 2008-07-08 Last modified: 2024-02-21 Method: ELECTRON MICROSCOPY (9 Å) Cite: The beginning of kinesin's force-generating cycle visualized at 9-A resolution. J.Cell Biol., 177, 2007
7LVR	KIF14[391-743] - ADP-AlFx closed state class in complex with a microtubule Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, ... Authors: Benoit, M.P.M.H, Asenjo, A.B, Paydar, M, Dhakal, S, Kwok, B, Sosa, H. Deposit date: 2021-02-26 Release date: 2021-05-05 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structural basis of mechano-chemical coupling by the mitotic kinesin KIF14. Nat Commun, 12, 2021
7LVQ	KIF14[391-743] - AMP-PNP closed state class in complex with a microtubule Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF14, ... Authors: Benoit, M.P.M.H, Asenjo, A.B, Paydar, M, Dhakal, S, Kwok, B, Sosa, H. Deposit date: 2021-02-26 Release date: 2021-05-05 Last modified: 2024-03-06 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: Structural basis of mechano-chemical coupling by the mitotic kinesin KIF14. Nat Commun, 12, 2021
7TR0	CaKip3[2-436] - AMP-PNP in complex with a microtubule Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein, ... Authors: Benoit, M.P.M.H, Asenjo, A.B, Hunter, B, Allingham, J, Sosa, H. Deposit date: 2022-01-27 Release date: 2022-07-20 Last modified: 2024-02-21 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Kinesin-8-specific loop-2 controls the dual activities of the motor domain according to tubulin protofilament shape. Nat Commun, 13, 2022
7TQX	CaKip3[2-482] - AMP-PNP in complex with a microtubule Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein, ... Authors: Benoit, M.P.M.H, Asenjo, A.B, Hunter, B, Allingham, J, Sosa, H. Deposit date: 2022-01-27 Release date: 2022-07-20 Last modified: 2024-02-21 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Kinesin-8-specific loop-2 controls the dual activities of the motor domain according to tubulin protofilament shape. Nat Commun, 13, 2022
7TR1	CaKip3[2-436]-L2-mutant(HsKHC) - AMP-PNP in complex with a microtubule Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein,Kinesin-1 heavy chain, ... Authors: Benoit, M.P.M.H, Asenjo, A.B, Hunter, B, Allingham, J.S, Sosa, H. Deposit date: 2022-01-27 Release date: 2022-07-20 Last modified: 2024-02-21 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Kinesin-8-specific loop-2 controls the dual activities of the motor domain according to tubulin protofilament shape. Nat Commun, 13, 2022
7TQY	CaKip3[2-482] - ADP-AlFx in complex with a microtubule Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, ... Authors: Benoit, M.P.M.H, Asenjo, A.B, Hunter, B, Allingham, J, Sosa, H. Deposit date: 2022-01-27 Release date: 2022-07-20 Last modified: 2024-02-21 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Kinesin-8-specific loop-2 controls the dual activities of the motor domain according to tubulin protofilament shape. Nat Commun, 13, 2022
7TR3	CaKip3[2-482] - AMP-PNP in complex with a dolastatin-10-stabilized tubulin ring Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein, ... Authors: Benoit, M.P.M.H, Asenjo, A.B, Hunter, B, Allingham, J.S, Sosa, H. Deposit date: 2022-01-27 Release date: 2022-07-20 Last modified: 2024-02-21 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Kinesin-8-specific loop-2 controls the dual activities of the motor domain according to tubulin protofilament shape. Nat Commun, 13, 2022
7TQZ	Apo CaKip3[2-482] in complex with a microtubule Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein, ... Authors: Benoit, M.P.M.H, Asenjo, A.B, Hunter, B, Allingham, J.S, Sosa, H. Deposit date: 2022-01-27 Release date: 2022-07-13 Last modified: 2024-02-21 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Kinesin-8-specific loop-2 controls the dual activities of the motor domain according to tubulin protofilament shape. Nat Commun, 13, 2022
7TR2	Apo CaKip3[2-436]-L2-mutant(HsKHC) in complex with a microtubule Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein,Kinesin-1 heavy chain, ... Authors: Benoit, M.P.M.H, Asenjo, A.B, Hunter, B, Allingham, J.S, Sosa, H. Deposit date: 2022-01-27 Release date: 2022-07-13 Last modified: 2024-02-21 Method: ELECTRON MICROSCOPY (3 Å) Cite: Kinesin-8-specific loop-2 controls the dual activities of the motor domain according to tubulin protofilament shape. Nat Commun, 13, 2022
5HNZ	Structural basis of backwards motion in kinesin-14: plus-end directed nKn669 in the nucleotide-free state Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Shigematsu, H, Yokoyama, T, Kikkawa, M, Shirouzu, M, Nitta, R. Deposit date: 2016-01-19 Release date: 2016-08-10 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (5.8 Å) Cite: Structural Basis of Backwards Motion in Kinesin-1-Kinesin-14 Chimera: Implication for Kinesin-14 Motility Structure, 24, 2016
5HNX	Structural basis of backwards motion in kinesin-14: minus-end directed nKn664 in the nucleotide-free state Descriptor: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Shigematsu, H, Yokoyama, T, Kikkawa, M, Shirouzu, M, Nitta, R. Deposit date: 2016-01-19 Release date: 2016-08-10 Last modified: 2024-03-27 Method: ELECTRON MICROSCOPY (6.6 Å) Cite: Structural Basis of Backwards Motion in Kinesin-1-Kinesin-14 Chimera: Implication for Kinesin-14 Motility Structure, 24, 2016

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