5YIG
 
 | | Crystal structure of Streptococcus pneumonia ParE with inhibitor | | Descriptor: | 1-ethyl-3-[5-[2-[(1S,5R)-3-methyl-3,8-diazabicyclo[3.2.1]octan-8-yl]-5-(2-oxidanylidene-3H-1,3,4-oxadiazol-5-yl)pyridin-3-yl]-4-[4-(trifluoromethyl)-1,3-thiazol-2-yl]pyridin-2-yl]urea, DNA topoisomerase 4 subunit B | | Authors: | Cherian, J, Tan, Y, Hill, J. | | Deposit date: | 2017-10-04 | | Release date: | 2018-09-05 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Discovery of dual GyrB/ParE inhibitors active against Gram-negative bacteria.
Eur J Med Chem, 157, 2018
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1NCS
 | | NMR STUDY OF SWI5 ZINC FINGER DOMAIN 1 | | Descriptor: | TRANSCRIPTIONAL FACTOR SWI5, ZINC ION | | Authors: | Dutnall, R.N, Neuhaus, D, Rhodes, D. | | Deposit date: | 1996-02-26 | | Release date: | 1996-06-10 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The solution structure of the first zinc finger domain of SWI5: a novel structural extension to a common fold.
Structure, 4, 1996
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8J6O
 | | transport T2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Green fluorescent protein (Fragment),SID1 transmembrane family member 2, ... | | Authors: | Jiang, D.H, Zhang, J.T. | | Deposit date: | 2023-04-26 | | Release date: | 2024-05-01 | | Last modified: | 2024-07-31 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Structural insights into double-stranded RNA recognition and transport by SID-1.
Nat.Struct.Mol.Biol., 31, 2024
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4MO7
 | | Crystal structure of superantigen PfiT | | Descriptor: | BETA-MERCAPTOETHANOL, MAGNESIUM ION, Transcriptional regulator I2 | | Authors: | Liu, L.H, Chen, H, Li, H.M. | | Deposit date: | 2013-09-11 | | Release date: | 2014-02-05 | | Method: | X-RAY DIFFRACTION (1.701 Å) | | Cite: | Pfit is a structurally novel Crohn's disease-associated superantigen.
Plos Pathog., 9, 2013
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6HP5
 | | ARBITRIUM PEPTIDE RECEPTOR FROM SPBETA PHAGE | | Descriptor: | GLY-MET-PRO-ARG-GLY-ALA, SPBc2 prophage-derived uncharacterized protein YopK, SULFATE ION | | Authors: | Marina, A, Gallego del Sol, F. | | Deposit date: | 2018-09-19 | | Release date: | 2019-02-20 | | Last modified: | 2019-04-17 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | Deciphering the Molecular Mechanism Underpinning Phage Arbitrium Communication Systems.
Mol.Cell, 74, 2019
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7P47
 | | Structure of the E3 ligase Smc5/Nse2 in complex with Ubc9-SUMO thioester mimetic | | Descriptor: | E3 SUMO-protein ligase MMS21, SUMO-conjugating enzyme UBC9, Structural maintenance of chromosomes protein 5, ... | | Authors: | Lascorz, J, Varejao, N, Reverter, D. | | Deposit date: | 2021-07-09 | | Release date: | 2021-11-24 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (3.314 Å) | | Cite: | Structural basis for the E3 ligase activity enhancement of yeast Nse2 by SUMO-interacting motifs.
Nat Commun, 12, 2021
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8SXM
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1KZ2
 | | Solution structure of the third helix of Antennapedia homeodomain derivative [W6F,W14F] | | Descriptor: | Antennapedia protein | | Authors: | Czajlik, A, Mesko, E, Penke, B, Perczel, A. | | Deposit date: | 2002-02-06 | | Release date: | 2002-02-20 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Investigation of penetratin peptides. Part 1. The environment dependent conformational properties of penetratin and two of its derivatives.
J.Pept.Sci., 8, 2002
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2GHQ
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1AVQ
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6HP3
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2GHT
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1KZ0
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5XNS
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1UPG
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2WTE
 | | The structure of the CRISPR-associated protein, Csa3, from Sulfolobus solfataricus at 1.8 angstrom resolution. | | Descriptor: | CSA3, DI(HYDROXYETHYL)ETHER | | Authors: | Lintner, N.G, Alsbury, D.L, Copie, V, Young, M.J, Lawrence, C.M. | | Deposit date: | 2009-09-15 | | Release date: | 2010-09-22 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The Structure of the Crispr-Associated Protein Csa3 Provides Insight Into the Regulation of the Crispr/Cas System.
J.Mol.Biol., 405, 2011
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1NOH
 | | The structure of bacteriophage phi29 scaffolding protein gp7 after prohead assembly | | Descriptor: | HEAD MORPHOGENESIS PROTEIN | | Authors: | Morais, M.C, Kanamaru, S, Badasso, M.O, Koti, J.S, Owen, B.L, McMurray, C.T, L Anderson, D, Rossmann, M.G. | | Deposit date: | 2003-01-16 | | Release date: | 2003-07-01 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Bacteriophage f29 scaffolding protein gp7 before and after prohead assembly
Nat.Struct.Biol., 10, 2003
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5UN7
 | | Structure of the human POT1-TPP1 telomeric complex | | Descriptor: | Adrenocortical dysplasia protein homolog, POTASSIUM ION, Protection of telomeres protein 1, ... | | Authors: | Rice, C, Doukov, T, Skordalakes, E. | | Deposit date: | 2017-01-30 | | Release date: | 2017-04-12 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural and functional analysis of the human POT1-TPP1 telomeric complex.
Nat Commun, 8, 2017
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1AX6
 | | SOLUTION STRUCTURE OF THE [AF]-C8-DG ADDUCT OPPOSITE A-2 DELETION SITE IN THE NARI HOT SPOT SEQUENCE CONTEXT; NMR, 6 STRUCTURES | | Descriptor: | 2-AMINOFLUORENE, DNA DUPLEX D(CTCGGC-[AF]G-CCATC)D(GATGGCCGAG) | | Authors: | Mao, B, Gorin, A.A, Gu, Z, Hingerty, B.E, Broyde, S, Patel, D.J. | | Deposit date: | 1997-10-30 | | Release date: | 1998-07-01 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the aminofluorene-intercalated conformer of the syn [AF]-C8-dG adduct opposite a--2 deletion site in the NarI hot spot sequence context.
Biochemistry, 36, 1997
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1D8B
 | | NMR STRUCTURE OF THE HRDC DOMAIN FROM SACCHAROMYCES CEREVISIAE RECQ HELICASE | | Descriptor: | SGS1 RECQ HELICASE | | Authors: | Liu, Z, Macias, M.J, Bottomley, M.J, Stier, G, Linge, J.P, Nilges, M, Bork, P, Sattler, M. | | Deposit date: | 1999-10-21 | | Release date: | 2000-01-10 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The three-dimensional structure of the HRDC domain and implications for the Werner and Bloom syndrome proteins.
Structure Fold.Des., 7, 1999
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2X8D
 | | Discovery of a Novel Class of triazolones as Checkpoint Kinase Inhibitors - Hit to Lead Exploration | | Descriptor: | 5-METHYL[1,2,4]TRIAZOLO[4,3-A]QUINOLIN-1(2H)-ONE, SERINE/THREONINE-PROTEIN KINASE CHK1, SULFATE ION | | Authors: | Read, J.A, Breed, J, Haye, H, McCall, E, Rowsell, S, Vallentine, A, White, A. | | Deposit date: | 2010-03-08 | | Release date: | 2010-08-11 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Discovery of a Novel Class of Triazolones as Checkpoint Kinase Inhibitors-Hit to Lead Exploration.
Bioorg.Med.Chem., 20, 2010
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1US6
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5XG2
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5XG3
 | | Crystal structure of the ATPgS-engaged Smc head domain with an extended coiled coil bound to the C-terminal domain of ScpA derived from Bacillus subtilis | | Descriptor: | COBALT (II) ION, Chromosome partition protein Smc, MAGNESIUM ION, ... | | Authors: | Shin, H.-C, Lee, H, Oh, B.-H. | | Deposit date: | 2017-04-11 | | Release date: | 2017-06-07 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structure of Full-Length SMC and Rearrangements Required for Chromosome Organization
Mol. Cell, 67, 2017
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2X8E
 | | Discovery of a Novel Class of triazolones as Checkpoint Kinase Inhibitors - Hit to Lead Exploration | | Descriptor: | 5-METHYL-8-PYRIDIN-4-YL[1,2,4]TRIAZOLO[4,3-A]QUINOLIN-1(2H)-ONE, SERINE/THREONINE-PROTEIN KINASE CHK1, SULFATE ION | | Authors: | Read, J.A, Breed, J, Haye, H, McCall, E, Rowsell, S, Vallentine, A, White, A. | | Deposit date: | 2010-03-09 | | Release date: | 2010-08-11 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Discovery of a Novel Class of Triazolones as Checkpoint Kinase Inhibitors-Hit to Lead Exploration.
Bioorg.Med.Chem., 20, 2010
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