PDB: 224004 resultsInfo pagesStatus searchChemie searchBIRD

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8PJQ	Crystal structure of the SAKe2BE protein Descriptor: SAKe2BE Authors: Wouters, S.M.L. Deposit date: 2023-06-23 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (1.15 Å) Cite: Computational design of the SAKe scaffold proteins To Be Published
8PRS	The structure of nvBagel4 Descriptor: nvBagel4 Authors: Vandebroek, L, Voet, A.R.D, Lee, X.Y. Deposit date: 2023-07-12 Release date: 2024-07-24 Method: X-RAY DIFFRACTION (1.75 Å) Cite: The structure of nvBagel4 To Be Published
8PTA	JNK1 covalently bound to BD837 cyclohexenone based inhibitor Descriptor: GLYCEROL, Mitogen-activated protein kinase 8, methyl (1R,3S)-1-methyl-3-[[3-[[3-methyl-4-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]carbamoyl]phenyl]carbamoyl]-4-oxidanylidene-cyclohexane-1-carboxylate Authors: Sok, P, Poti, A, Remenyi, A. Deposit date: 2023-07-13 Release date: 2024-07-24 Method: X-RAY DIFFRACTION (2.41 Å) Cite: Tunable c-Jun N-terminal kinase (JNK) inhibitors that target a specific cysteine by a reversible covalent bond To Be Published
8PU2	Structure of the antitoxin ATfaRel2 Descriptor: Antitoxin ATfaRel2, antidote of FaRel2, PHOSPHATE ION Authors: Garcia-Pino, A, Talavera Perez, A, Dominguez Molina, L. Deposit date: 2023-07-16 Release date: 2024-07-24 Method: X-RAY DIFFRACTION (1.24 Å) Cite: Structure of the antitoxin ATfaRel2 To Be Published
8PJW	Crystal structure of the computationally designed SAKe6FE protein Descriptor: SAKe6FE Authors: Wouters, S.M.L. Deposit date: 2023-06-23 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Computational design of the SAKe scaffold proteins To Be Published
8PMN	transcription factor BARHL2 bound to DNA sequences Descriptor: BarH-like 2 homeobox protein, DNA Authors: Morgunova, E, Popov, A, Yin, Y, Taipale, J. Deposit date: 2023-06-29 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (1.3 Å) Cite: transcription factor BARHL2 bound to DNA sequences To Be Published
8PU3	Complex of the toxin/antitoxin FaRel2/ATfaRel2 Descriptor: ATfaRel2, FaRel2 Authors: Garcia-Pino, A, Talavera Perez, A, Dominguez Molina, L. Deposit date: 2023-07-16 Release date: 2024-07-24 Method: X-RAY DIFFRACTION (2.17 Å) Cite: Structure of the toxin/antitoxin complex FaRel2/ATfaRel2 To Be Published
4XOR	Tailspike protein double mutant D339N/E372Q of E. coli bacteriophage HK620 in complex with pentasaccharide Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FORMIC ACID, SODIUM ION, ... Authors: Gohlke, U, Broeker, N.K, Heinemann, U, Seckler, R, Barbirz, S. Deposit date: 2015-01-16 Release date: 2016-01-27 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Enthalpic cost of water removal from a hydrophobic glucose binding cavity on HK620 tailspike protein. to be published
8PN4	transcription factor BARHL2 bound to DNA sequences Descriptor: ACETATE ION, BarH-like 2 homeobox protein, DNA Authors: Morgunova, E, Yin, Y, Popov, A, Taipale, J. Deposit date: 2023-06-29 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (2.6 Å) Cite: transcription factor BARHL2 bound to DNA sequences To Be Published
7TTX	Crystal structure of potent neutralizing antibody 10-40 in complex with Sarbecovirus bat RaTG13 receptor-binding domain Descriptor: 1040 heavy chain, 1040 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Reddem, E.R, Shapiro, L. Deposit date: 2022-02-02 Release date: 2022-04-27 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.8 Å) Cite: An antibody class with a common CDRH3 motif broadly neutralizes sarbecoviruses. Sci Transl Med, 14, 2022
8PMW	HEV gt3 P domain in complex with glycan-sensitive nAb p60.1 Descriptor: ACETATE ION, Capsid protein, SULFATE ION, ... Authors: Ssebyatika, G, Krey, T. Deposit date: 2023-06-29 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (1.98 Å) Cite: A novel class of broadly neutralizing hepatitis E virus-specific human antibodies To Be Published
4XQ5	Human-infecting H10N8 influenza virus retains strong preference for avian-type receptors Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ... Authors: Tzarum, N, Zhang, H, Zhu, X, Wilson, I.A. Deposit date: 2015-01-19 Release date: 2015-04-01 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.592 Å) Cite: A Human-Infecting H10N8 Influenza Virus Retains a Strong Preference for Avian-type Receptors. Cell Host Microbe, 17, 2015
8PQO	PITP in complex with the inhibitor VT01545 Descriptor: GLYCEROL, IMIDAZOLE, Inhibitor VT01545, ... Authors: Boura, E, Eisenreichova, A. Deposit date: 2023-07-11 Release date: 2024-05-08 Last modified: 2024-07-17 Method: X-RAY DIFFRACTION (2.3 Å) Cite: PITP in complex with the inhibitor VT01545 To Be Published
6ZJX	Cold-adapted beta-D-galactosidase from Arthrobacter sp. 32cB mutant D207A in complex with saccharose Descriptor: ACETATE ION, Beta-galactosidase, MALONATE ION, ... Authors: Rutkiewicz, M, Bujacz, A, Bujacz, G. Deposit date: 2020-06-29 Release date: 2020-08-05 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.206 Å) Cite: Mapping the Transglycosylation Relevant Sites of Cold-Adapted beta-d-Galactosidase fromArthrobactersp. 32cB. Int J Mol Sci, 21, 2020
8AVA	Leukotriene A4 hydrolase in complex with 4-(4-benzylphenyl)-oxazol-2-amine Descriptor: 4-[4-(phenylmethyl)phenyl]-1,3-oxazol-2-amine, ACETATE ION, GLYCEROL, ... Authors: Teder, T, Haeggstrom, J.Z. Deposit date: 2022-08-26 Release date: 2023-05-03 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.354 Å) Cite: Modulation of the 5-Lipoxygenase Pathway by Chalcogen-Containing Inhibitors of Leukotriene A 4 Hydrolase. Int J Mol Sci, 24, 2023
4XX4	Renin in complex with (4S)-4-isopropyl-4-methyl-6-oxo-1-(3-(2-oxo-4-phenylpyrrolidin-1-yl)benzyl)tetrahydropyrimidin-2(1H)-iminium Descriptor: (2Z,6S)-2-imino-6-methyl-3-{3-[(4R)-2-oxo-4-phenylpyrrolidin-1-yl]benzyl}-6-(propan-2-yl)tetrahydropyrimidin-4(1H)-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin Authors: Orth, P. Deposit date: 2015-01-29 Release date: 2015-02-18 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Iminopyrimidinones: a novel pharmacophore for the development of orally active renin inhibitors. Bioorg. Med. Chem. Lett., 25, 2015
8PJL	DNA duplex forming base triplets in minor groove Descriptor: DNA (5'-D(*AP*AP*CP*TP*GP*AP*GP*AP*GP*AP*CP*GP*TP*A)-3'), DNA (5'-D(*TP*AP*CP*GP*TP*CP*TP*CP*TP*CP*AP*GP*TP*C)-3'), MAGNESIUM ION, ... Authors: Abdullrahman, A, Cardin, C.J, Hall, J.P. Deposit date: 2023-06-23 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (2 Å) Cite: DNA duplex with triplets bases in minor groove To Be Published
8PJ9	Cas9 bound to cognate DNA, Streptococcus thermophilus DGCC 7710 CRISPR3 system Descriptor: CRISPR-associated endonuclease Cas9, DNA oligoduplex, non-target strand, ... Authors: Sasnauskas, G, Gaizauskaite, U, Tamulaitiene, G. Deposit date: 2023-06-23 Release date: 2024-07-10 Method: ELECTRON MICROSCOPY (3.24 Å) Cite: Structural basis for spacer acquisition in a type II-A CRISPR-Cas system To Be Published
8PN0	HEV gt3 P domain in complex with glycan-sensitive nAb p60.12 Descriptor: Capsid protein, Fab_p60.12-HC, Fab_p60.12-LC Authors: Ssebyatika, G, Krey, T. Deposit date: 2023-06-29 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (2.072 Å) Cite: A novel class of broadly neutralizing hepatitis E virus-specific human antibodies To Be Published
8Q3W	ATP-bound IstB in complex to duplex DNA Descriptor: ADENOSINE-5'-TRIPHOSPHATE, DNA (48-MER) Target DNA FW, DNA (48-MER) Traget DNA Rv, ... Authors: de la Gandara, A, Spinola-Amilibia, M, Araujo-Bazan, L, Nunez-Ramirez, R, Berger, J.M, Arias-Palomo, E. Deposit date: 2023-08-04 Release date: 2024-07-10 Method: ELECTRON MICROSCOPY (3.18 Å) Cite: Molecular basis for transposase activation by a dedicated AAA+ ATPase. Nature, 630, 2024
8PT9	JNK1 covalently bound to BD838 cyclohexenone based inhibitor Descriptor: Mitogen-activated protein kinase 8, methyl (1S,3S)-1-methyl-3-[[3-[[3-methyl-4-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]carbamoyl]phenyl]carbamoyl]-4-oxidanylidene-cyclohexane-1-carboxylate Authors: Sok, P, Poti, A, Remenyi, A. Deposit date: 2023-07-13 Release date: 2024-07-24 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Tunable c-Jun N-terminal kinase (JNK) inhibitors that target a specific cysteine by a reversible covalent bond To Be Published
8PRJ	The structure of v31Bagel8 Descriptor: CHLORIDE ION, v31Bagel8 Authors: Vandebroek, L, Voet, A.R.D, Lee, X.Y. Deposit date: 2023-07-12 Release date: 2024-07-24 Method: X-RAY DIFFRACTION (1.4 Å) Cite: The structure of v13Bagel8 To Be Published
8PX6	Hepatitis B core protein with bound SLLGRM-dimer Descriptor: External core antigen, SLLGRM-dimer Authors: Makbul, C, Khayenko, V, Maric, M.H, Bottcher, B. Deposit date: 2023-07-22 Release date: 2024-07-31 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Peptide dimers aggregate Hepatitis B core proteins in live cells To Be Published
4XBQ	Crystal Structure of Human Galectin-7 in Complex with Type 1 N-acetyllactosamine Descriptor: Galectin-7, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose Authors: Hsieh, T.J, Lin, H.Y, Lin, C.H. Deposit date: 2014-12-17 Release date: 2015-05-20 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.234 Å) Cite: Structural Basis Underlying the Binding Preference of Human Galectins-1, -3 and -7 for Gal beta 1-3/4GlcNAc. Plos One, 10, 2015
8PJZ	Crystal structure of the computationally designed SAKe6EEtal protein Descriptor: SAKe6EEtal Authors: Wouters, S.M.L. Deposit date: 2023-06-23 Release date: 2024-07-10 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Computational design of the SAKe scaffold proteins To Be Published

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