7W8D
 
 | | The structure of Deinococcus radiodurans RuvC | | Descriptor: | Crossover junction endodeoxyribonuclease RuvC, MAGNESIUM ION | | Authors: | Cheng, K. | | Deposit date: | 2021-12-07 | | Release date: | 2022-08-17 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.75016141 Å) | | Cite: | Biochemical and Structural Study of RuvC and YqgF from Deinococcus radiodurans.
Mbio, 13, 2022
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5IZC
 | | Trypanosoma brucei PTR1 in complex with inhibitor F032 | | Descriptor: | ACETATE ION, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | Authors: | Pozzi, C, Landi, G, Di Pisa, F, Mangani, S. | | Deposit date: | 2016-03-25 | | Release date: | 2017-04-05 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery.
ACS Omega, 2, 2017
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4YYX
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8IAH
 | | Structure of mammalian spectrin-actin junctional complex of membrane skeleton, State I, Global map | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | | Authors: | Li, N, Chen, S, Gao, N. | | Deposit date: | 2023-02-08 | | Release date: | 2023-05-03 | | Last modified: | 2023-05-10 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural basis of membrane skeleton organization in red blood cells.
Cell, 186, 2023
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8IAI
 | | Structure of mammalian spectrin-actin junctional complex of membrane skeleton, State II, Global map | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | | Authors: | Li, N, Chen, S, Gao, N. | | Deposit date: | 2023-02-08 | | Release date: | 2023-05-03 | | Last modified: | 2023-05-10 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structural basis of membrane skeleton organization in red blood cells.
Cell, 186, 2023
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7KUZ
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5A1J
 | | Periplasmic Binding Protein CeuE in complex with ferric 4-LICAM | | Descriptor: | ENTEROCHELIN UPTAKE PERIPLASMIC BINDING PROTEIN, FE (III) ION, N,N'-butane-1,4-diylbis(2,3-dihydroxybenzamide) | | Authors: | Raines, D.J, Moroz, O.V, Wilson, K.S, Duhme-Klair, A.K. | | Deposit date: | 2015-04-30 | | Release date: | 2015-05-13 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Interactions of a Periplasmic Binding Protein with a Tetradentate Siderophore Mimic.
Angew.Chem.Int.Ed.Engl., 52, 2013
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5W17
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1AVG
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5HBI
 | | SCAPHARCA DIMERIC HEMOGLOBIN, MUTANT T72I, CO-LIGANDED FORM | | Descriptor: | CARBON MONOXIDE, HEMOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Royer Junior, W.E. | | Deposit date: | 1998-06-24 | | Release date: | 1998-11-11 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Mutational destabilization of the critical interface water cluster in Scapharca dimeric hemoglobin: structural basis for altered allosteric activity.
J.Mol.Biol., 284, 1998
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7KE9
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1BL5
 | | ISOCITRATE DEHYDROGENASE FROM E. COLI SINGLE TURNOVER LAUE STRUCTURE OF RATE-LIMITED PRODUCT COMPLEX, 10 MSEC TIME RESOLUTION | | Descriptor: | 2-OXOGLUTARIC ACID, ISOCITRATE DEHYDROGENASE, MAGNESIUM ION, ... | | Authors: | Stoddard, B.L, Cohen, B, Brubaker, M, Mesecar, A, Koshland Junior, D.E. | | Deposit date: | 1998-07-23 | | Release date: | 1999-05-04 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Millisecond Laue structures of an enzyme-product complex using photocaged substrate analogs.
Nat.Struct.Biol., 5, 1998
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7KEB
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7KDH
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2RRM
 | | Interplay between phosphatidyl-inositol-phosphates and claudins upon binding to the 1st PDZ domain of zonula occludens 1 | | Descriptor: | Tight junction protein ZO-1 | | Authors: | Hiroaki, H, Satomura, K, Goda, N, Umetsu, Y, Taniguchi, R, Ikegami, T, Furuse, M. | | Deposit date: | 2011-01-06 | | Release date: | 2011-05-25 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | 1H, 13C, and 15N resonance assignment of the first PDZ domain of mouse ZO-1
Biomol.Nmr Assign., 5, 2011
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7KDI
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7KEA
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7KDG
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7KDL
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7KE8
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5V7I
 | | Crystal structure of homo sapiens serine hydroxymethyltransferase 2 (mitochondrial) (SHMT2), in complex with glycine, PLP and folate-competitive pyrazolopyran inhibitor: 6-amino-4-isopropyl-3-methyl-4-(3-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile | | Descriptor: | (4R)-6-amino-3-methyl-4-(propan-2-yl)-4-[3-(pyrrolidin-1-yl)-5-(trifluoromethyl)phenyl]-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | Authors: | Ducker, G.S, Ghergurovich, J.M, Mainolfi, N, Suri, V, Jeong, S, Friedman, A, Manfredi, M, Kim, H, Rabinowitz, J.D. | | Deposit date: | 2017-03-20 | | Release date: | 2017-10-11 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.47 Å) | | Cite: | Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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7KDJ
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7KE4
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7KDK
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7KEC
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