1W0R
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2ZGR
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2VDT
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![BU of 2vdt by Molmil](/molmil-images/mine/2vdt) | Crystallographic structure of Levansucrase from Bacillus subtilis mutant S164A | Descriptor: | CALCIUM ION, LEVANSUCRASE | Authors: | Ortiz-Soto, M.E, Rivera, M, Rudino-Pinera, E, Olvera, C, Lopez-Munguia, A. | Deposit date: | 2007-10-11 | Release date: | 2008-07-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Selected Mutations in Bacillus Subtilis Levansucrase Semi-Conserved Regions Affecting its Biochemical Properties Protein Eng.Des.Sel., 21, 2008
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2VDY
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![BU of 2vdy by Molmil](/molmil-images/mine/2vdy) | Crystal structure of the reactive loop cleaved Corticosteroid Binding Globulin complexed with Cortisol | Descriptor: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, CORTICOSTEROID-BINDING GLOBULIN | Authors: | Zhou, A, Wei, Z, Read, R.J. | Deposit date: | 2007-10-13 | Release date: | 2008-05-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The S-to-R Transition of Corticosteroid-Binding Globulin and the Mechanism of Hormone Release. J.Mol.Biol., 380, 2008
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2ZWL
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![BU of 2zwl by Molmil](/molmil-images/mine/2zwl) | Human factor viia-tissue factor complexed with highly selective peptide inhibitor | Descriptor: | 2-[[(2R)-1-[[(2S)-5-amino-1-[(4-carbamimidoylphenyl)methylamino]-1,5-dioxo-pentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxo-propan-2-yl]sulfamoyl]ethanoic acid, CALCIUM ION, Factor VII heavy chain, ... | Authors: | Kadono, S, Sakamoto, A, Kikuchi, Y, Oh-Eda, M, Yabuta, N, Koga, T, Hattori, K, Shiraishi, T, Haramura, M, Sato, H, Ohta, M, Kozono, T. | Deposit date: | 2008-12-16 | Release date: | 2009-01-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Human factor viia-tissue factor complexed with highly selective peptide inhibitor To be Published
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1VWC
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![BU of 1vwc by Molmil](/molmil-images/mine/1vwc) | STREPTAVIDIN-CYCLO-AC-[CHPQFC]-NH2, PH 2.0 | Descriptor: | PEPTIDE LIGAND CONTAINING HPQ, STREPTAVIDIN | Authors: | Katz, B.A, Cass, R.T. | Deposit date: | 1997-03-03 | Release date: | 1998-03-18 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | In crystals of complexes of streptavidin with peptide ligands containing the HPQ sequence the pKa of the peptide histidine is less than 3.0. J.Biol.Chem., 272, 1997
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1VWD
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![BU of 1vwd by Molmil](/molmil-images/mine/1vwd) | STREPTAVIDIN-CYCLO-AC-[CHPQFC]-NH2, PH 3.0 | Descriptor: | PEPTIDE LIGAND CONTAINING HPQ, STREPTAVIDIN | Authors: | Katz, B.A, Cass, R.T. | Deposit date: | 1997-03-03 | Release date: | 1998-03-18 | Last modified: | 2011-11-16 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | In crystals of complexes of streptavidin with peptide ligands containing the HPQ sequence the pKa of the peptide histidine is less than 3.0. J.Biol.Chem., 272, 1997
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2XV3
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![BU of 2xv3 by Molmil](/molmil-images/mine/2xv3) | Pseudomonas aeruginosa Azurin with mutated metal-binding loop sequence (CAAAAHAAAAM), chemically reduced, pH5.3 | Descriptor: | AZURIN, COPPER (I) ION | Authors: | Li, C, Sato, K, Monari, S, Salard, I, Sola, M, Banfield, M.J, Dennison, C. | Deposit date: | 2010-10-22 | Release date: | 2010-12-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Metal-Binding Loop Length is a Determinant of the Pka of a Histidine Ligand at a Type 1 Copper Site Inorg.Chem., 50, 2011
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1W0T
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![BU of 1w0t by Molmil](/molmil-images/mine/1w0t) | hTRF1 DNA-binding domain in complex with telomeric DNA. | Descriptor: | 5'-D(*CP*TP*GP*TP*TP*AP*GP*GP*GP*TP *TP*AP*GP*GP*GP*TP*TP*AP*G)-3', 5'-D(*TP*CP*TP*AP*AP*CP*CP*CP*TP*AP *AP*CP*CP*CP*TP*AP*AP*CP*A)-3', TELOMERIC REPEAT BINDING FACTOR 1 | Authors: | Court, R.I, Chapman, L.M, Fairall, L, Rhodes, D. | Deposit date: | 2004-06-11 | Release date: | 2004-12-22 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | How the Human Telomeric Proteins Trf1 and Trf2 Recognize Telomeric DNA: A View from High-Resolution Crystal Structures Embo Rep., 6, 2005
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6IIV
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![BU of 6iiv by Molmil](/molmil-images/mine/6iiv) | Crystal structure of the human thromboxane A2 receptor bound to daltroban | Descriptor: | 2-[4-[2-[(4-chlorophenyl)sulfonylamino]ethyl]phenyl]ethanoic acid, CHOLESTEROL, GLYCEROL, ... | Authors: | Fan, H, Zhao, Q, Wu, B. | Deposit date: | 2018-10-07 | Release date: | 2018-12-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for ligand recognition of the human thromboxane A2receptor. Nat. Chem. Biol., 15, 2019
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1VCQ
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2XN9
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![BU of 2xn9 by Molmil](/molmil-images/mine/2xn9) | Crystal structure of the ternary complex between human T cell receptor, staphylococcal enterotoxin H and human major histocompatibility complex class II | Descriptor: | ENTEROTOXIN H, GLYCEROL, HEMAGGLUTININ, ... | Authors: | Saline, M, Rodstrom, K.E.J, Fischer, G, Orekhov, V.Y, Karlsson, B.G, Lindkvist-Petersson, K. | Deposit date: | 2010-07-31 | Release date: | 2010-11-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The Structure of Superantigen Complexed with Tcr and Mhc Reveals Novel Insights Into Superantigenic T Cell Activation. Nat.Commun., 1, 2010
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2UWP
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![BU of 2uwp by Molmil](/molmil-images/mine/2uwp) | Factor Xa inhibitor complex | Descriptor: | 2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}ETHANESULFONAMIDE, CALCIUM ION, COAGULATION FACTOR X, ... | Authors: | Young, R.J, Brown, D, Burns-Kurtis, C.L, Chan, C, Convery, M.A, Hubbard, J.A, Kelly, H.A, Pateman, A.J, Patikis, A, Senger, S, Shah, G.P, Toomey, J.R, Watson, N.S, Zhou, P, Thorpe, J.H. | Deposit date: | 2007-03-22 | Release date: | 2007-05-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Selective and Dual Action Orally Active Inhibitors of Thrombin and Factor Xa. Bioorg.Med.Chem.Lett., 17, 2007
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3L4W
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![BU of 3l4w by Molmil](/molmil-images/mine/3l4w) | Crystal complex of N-terminal Human Maltase-Glucoamylase with miglitol | Descriptor: | (2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Sim, L, Rose, D.R. | Deposit date: | 2009-12-21 | Release date: | 2010-02-09 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | New glucosidase inhibitors from an ayurvedic herbal treatment for type 2 diabetes: structures and inhibition of human intestinal maltase-glucoamylase with compounds from Salacia reticulata. Biochemistry, 49, 2010
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2XLA
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![BU of 2xla by Molmil](/molmil-images/mine/2xla) | Structure and metal-loading of a soluble periplasm cupro-protein: Cu- CucA-closed | Descriptor: | COPPER (II) ION, SLL1785 PROTEIN, UREA | Authors: | Waldron, K.J, Firbank, S.J, Dainty, S.J, Perez-Rama, M, Tottey, S, Robinson, N.J. | Deposit date: | 2010-07-20 | Release date: | 2010-08-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Structure and Metal Loading of a Soluble Periplasm Cuproprotein. J.Biol.Chem., 285, 2010
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6IRF
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![BU of 6irf by Molmil](/molmil-images/mine/6irf) | Structure of the human GluN1/GluN2A NMDA receptor in the glutamate/glycine-bound state at pH 6.3, Class I | Descriptor: | Glutamate receptor ionotropic, NMDA 1, NMDA 2A | Authors: | Zhang, J, Chang, S, Zhang, X, Zhu, S. | Deposit date: | 2018-11-12 | Release date: | 2019-01-16 | Last modified: | 2019-06-05 | Method: | ELECTRON MICROSCOPY (5.1 Å) | Cite: | Structural Basis of the Proton Sensitivity of Human GluN1-GluN2A NMDA Receptors Cell Rep, 25, 2018
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8Q5Z
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3KMF
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2XMD
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![BU of 2xmd by Molmil](/molmil-images/mine/2xmd) | G117H mutant of human butyrylcholinesterase in complex with echothiophate | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Nachon, F, Carletti, E, Wandhammer, M, Nicolet, Y, Schopfer, L.M, Masson, P, Lockridge, O. | Deposit date: | 2010-07-27 | Release date: | 2010-12-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | X-Ray Crystallographic Snapshots of Reaction Intermediates in the G117H Mutant of Human Butyrylcholinesterase, a Nerve Agent Target Engineered Into a Catalytic Bioscavenge Biochem.J., 434, 2011
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3KZO
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![BU of 3kzo by Molmil](/molmil-images/mine/3kzo) | Crystal structure of N-acetyl-L-ornithine transcarbamylase complexed with carbamyl phosphate and N-acetyl-L-norvaline | Descriptor: | GLYCEROL, N-ACETYL-L-NORVALINE, N-acetylornithine carbamoyltransferase, ... | Authors: | Shi, D, Yu, X, Allewell, N.M, Tuchman, M. | Deposit date: | 2009-12-08 | Release date: | 2010-03-31 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structures of N-acetylornithine transcarbamoylase from Xanthomonas campestris complexed with substrates and substrate analogs imply mechanisms for substrate binding and catalysis. Proteins, 64, 2006
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6ITC
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![BU of 6itc by Molmil](/molmil-images/mine/6itc) | Structure of a substrate engaged SecA-SecY protein translocation machine | Descriptor: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, ... | Authors: | Ma, C.Y, Wu, X.F, Sun, D.J, Park, E.Y, Rapoport, T.A, Gao, N, Long, L. | Deposit date: | 2018-11-21 | Release date: | 2019-06-12 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.45 Å) | Cite: | Structure of the substrate-engaged SecA-SecY protein translocation machine. Nat Commun, 10, 2019
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2XQF
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![BU of 2xqf by Molmil](/molmil-images/mine/2xqf) | X-ray Structure of human butyrylcholinesterase inhibited by racemic VX | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Wandhammer, M, Carletti, E, Gillon, E, Masson, P, Goeldner, M, Noort, D, Nachon, F. | Deposit date: | 2010-09-02 | Release date: | 2011-03-23 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Study of the Complex Stereoselectivity of Human Butyrylcholinesterase for the Neurotoxic V-Agents. J.Biol.Chem., 286, 2011
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6IE3
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![BU of 6ie3 by Molmil](/molmil-images/mine/6ie3) | Crystal structure of methyladenine demethylase | Descriptor: | ETHANOL, MANGANESE (II) ION, Nucleic acid dioxygenase ALKBH1 | Authors: | Tian, L.F, Tang, Q, Chen, Z.Z, Yan, X.X. | Deposit date: | 2018-09-13 | Release date: | 2019-09-18 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structural basis of nucleic acid recognition and 6mA demethylation by human ALKBH1. Cell Res., 30, 2020
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3L4Y
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![BU of 3l4y by Molmil](/molmil-images/mine/3l4y) | Crystal complex of N-terminal Human Maltase-Glucoamylase with NR4-8II | Descriptor: | (1S,2R,3S,4R)-1-{(1S)-2-[(2R,3S,4S)-3,4-dihydroxy-2-(hydroxymethyl)tetrahydrothiophenium-1-yl]-1-hydroxyethyl}-2,3,4,5-tetrahydroxypentyl sulfate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Sim, L, Rose, D.R. | Deposit date: | 2009-12-21 | Release date: | 2010-02-09 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | New glucosidase inhibitors from an ayurvedic herbal treatment for type 2 diabetes: structures and inhibition of human intestinal maltase-glucoamylase with compounds from Salacia reticulata. Biochemistry, 49, 2010
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2XP6
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![BU of 2xp6 by Molmil](/molmil-images/mine/2xp6) | DISCOVERY OF CELL-ACTIVE PHENYL-IMIDAZOLE PIN1 INHIBITORS BY STRUCTURE-GUIDED FRAGMENT EVOLUTION | Descriptor: | 2-(3-CHLORO-PHENYL)-5-METHYL-1H-IMIDAZOLE-4-CARBOXYLIC ACID, DODECAETHYLENE GLYCOL, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1 | Authors: | Potter, A, Oldfield, V, Nunns, C, Fromont, C, Ray, S, Northfield, C.J, Bryant, C.J, Scrace, S.F, Robinson, D, Matossova, N, Baker, L, Dokurno, P, Surgenor, A.E, Davis, B.E, Richardson, C.M, Murray, J.B, Moore, J.D. | Deposit date: | 2010-08-25 | Release date: | 2011-01-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Discovery of Cell-Active Phenyl-Imidazole Pin1 Inhibitors by Structure-Guided Fragment Evolution. Bioorg.Med.Chem.Lett., 20, 2010
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