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8XVT
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BU of 8xvt by Molmil
The core subcomplex of human NuA4/TIP60 complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ...
Authors:Chen, K, Wang, L, Yu, Z, Yu, J, Ren, Y, Wang, Q, Xu, Y.
Deposit date:2024-01-15
Release date:2024-07-24
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of the human TIP60 complex.
Nat Commun, 15, 2024
9C0C
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BU of 9c0c by Molmil
E.coli GroEL apoenzyme
Descriptor: 60 kDa chaperonin
Authors:Watson, E.R, Lander, G.C.
Deposit date:2024-05-25
Release date:2024-08-07
Last modified:2024-08-14
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:Bis-sulfonamido-2-phenylbenzoxazoles Validate the GroES/EL Chaperone System as a Viable Antibiotic Target.
J.Am.Chem.Soc., 146, 2024
8W0I
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BU of 8w0i by Molmil
Cryo-EM structure of the human MCM2-7 heterohexamer
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA replication licensing factor MCM2, ...
Authors:Yang, R, Hunker, O, Bleichert, F.
Deposit date:2024-02-13
Release date:2024-10-02
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Multiple pathways for licensing human replication origins
To Be Published
8X7U
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BU of 8x7u by Molmil
MCM in complex with dsDNA in presence of ATP.
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, mini-chromosome maintenance complex 3
Authors:Ma, J, Yi, G, Ye, M, MacGregor-Chatwin, C, Sheng, Y, Lu, Y, Li, M, Gilbert, R.J.C, Zhang, P.
Deposit date:2023-11-25
Release date:2024-01-17
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:MCM in complex with dsDNA in presence of ATP
To Be Published
5KZ7
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BU of 5kz7 by Molmil
Mark2 complex with 7-[(1S)-1-(4-fluorophenyl)ethyl]-5,5-dimethyl-2-(3-pyridylamino)pyrrolo[2,3-d]pyrimidin-6-one
Descriptor: 7-[(1~{S})-1-(4-fluorophenyl)ethyl]-5,5-dimethyl-2-(pyridin-3-ylamino)pyrrolo[2,3-d]pyrimidin-6-one, Serine/threonine-protein kinase MARK2
Authors:Su, H.P, Munshi, S.K.
Deposit date:2016-07-23
Release date:2017-05-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure guided design of a series of selective pyrrolopyrimidinone MARK inhibitors.
Bioorg. Med. Chem. Lett., 27, 2017
8W0G
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BU of 8w0g by Molmil
Cryo-EM structure of a human MCM2-7 dimer
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA replication licensing factor MCM2, ...
Authors:Yang, R, Hunker, O, Bleichert, F.
Deposit date:2024-02-13
Release date:2024-10-02
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Multiple pathways for licensing human replication origins
To Be Published
1YXA
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BU of 1yxa by Molmil
Serpina3n, a murine orthologue of human antichymotrypsin
Descriptor: serine (or cysteine) proteinase inhibitor, clade A, member 3N
Authors:Horvath, A.J, Irving, J.A, Law, R.H, Rossjohn, J, Bottomley, S.P, Quinsey, N.S, Pike, R.N, Coughlin, P.B, Whisstock, J.C.
Deposit date:2005-02-20
Release date:2005-09-06
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The murine orthologue of human antichymotrypsin: a structural paradigm for clade A3 serpins.
J.Biol.Chem., 280, 2005
8XVG
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BU of 8xvg by Molmil
Structure of human NuA4/TIP60 complex
Descriptor: ACTB protein (Fragment), ADENOSINE-5'-DIPHOSPHATE, Actin-like protein 6A, ...
Authors:Chen, K, Wang, L, Yu, Z, Yu, J, Ren, Y, Wang, Q, Xu, Y.
Deposit date:2024-01-15
Release date:2024-07-24
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (9.4 Å)
Cite:Structure of the human TIP60 complex.
Nat Commun, 15, 2024
9BOQ
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BU of 9boq by Molmil
Human p97/VCP structure with a triazole inhibitor (NSC799462/dodecamer)
Descriptor: 3-(2,6-difluoro-4-{[(4P)-5-{[(2S)-hexan-2-yl]sulfanyl}-4-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl]methoxy}phenyl)prop-2-yn-1-yl (1-methylpiperidin-4-yl)carbamate, ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase
Authors:Nandi, P, DeVore, K, Chiu, P.-L.
Deposit date:2024-05-05
Release date:2024-08-21
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Mechanism of allosteric inhibition of human p97/VCP ATPase and its disease mutant by triazole inhibitors.
Commun Chem, 7, 2024
8SNH
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BU of 8snh by Molmil
cytochrome bc1-cbb3 supercomplex from Pseudomonas aeruginosa
Descriptor: (2R)-2-(methoxymethyl)-4-{[(25R)-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, CALCIUM ION, COPPER (II) ION, ...
Authors:Di Trani, J.M, Rubinstein, J.L.
Deposit date:2023-04-27
Release date:2023-10-11
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structure of the bc 1 - cbb 3 respiratory supercomplex from Pseudomonas aeruginosa.
Proc.Natl.Acad.Sci.USA, 120, 2023
8SHD
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BU of 8shd by Molmil
CCT G beta 5 complex closed state 10
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ...
Authors:Wang, S, Sass, M, Willardson, B.M, Shen, P.S.
Deposit date:2023-04-13
Release date:2023-10-25
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller.
Mol.Cell, 83, 2023
8SMR
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BU of 8smr by Molmil
cytochrome bc1-cbb3 supercomplex from Pseudomonas aeruginosa
Descriptor: (2R)-2-(methoxymethyl)-4-{[(25R)-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, CALCIUM ION, COPPER (II) ION, ...
Authors:Di Trani, J.M, Rubinstein, J.L.
Deposit date:2023-04-26
Release date:2023-10-11
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structure of the bc 1 - cbb 3 respiratory supercomplex from Pseudomonas aeruginosa.
Proc.Natl.Acad.Sci.USA, 120, 2023
8YD8
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BU of 8yd8 by Molmil
Structure of FADD/Caspase-8/cFLIP death effector domain assembly
Descriptor: CASP8 and FADD-like apoptosis regulator subunit p43, Caspase-8, FAS-associated death domain protein
Authors:Lin, S.-C, Yang, C.-Y.
Deposit date:2024-02-19
Release date:2024-05-15
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Deciphering DED assembly mechanisms in FADD-procaspase-8-cFLIP complexes regulating apoptosis.
Nat Commun, 15, 2024
8SHP
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BU of 8shp by Molmil
CCT G beta 5 complex closed state 13
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ...
Authors:Wang, S, Sass, M, Willardson, B.M, Shen, P.S.
Deposit date:2023-04-14
Release date:2023-10-25
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller.
Mol.Cell, 83, 2023
5L94
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BU of 5l94 by Molmil
The 2.25 A crystal structure of CYP109E1 from Bacillus megaterium in complex with testosterone
Descriptor: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, TESTOSTERONE
Authors:Jozwik, I.K, Thunnissen, A.M.W.H.
Deposit date:2016-06-09
Release date:2016-10-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis of steroid binding and oxidation by the cytochrome P450 CYP109E1 from Bacillus megaterium.
Febs J., 283, 2016
8SHA
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BU of 8sha by Molmil
CCT-G beta 5 complex closed state 4
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ...
Authors:Wang, S, Sass, M, Willardson, B.M, Shen, P.S.
Deposit date:2023-04-13
Release date:2023-10-25
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller.
Mol.Cell, 83, 2023
8SHO
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BU of 8sho by Molmil
CCT G beta 5 complex close state 11
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ...
Authors:Wang, S, Sass, M, Willardson, B.M, Shen, P.S.
Deposit date:2023-04-14
Release date:2023-10-25
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller.
Mol.Cell, 83, 2023
8SHE
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BU of 8she by Molmil
CCT-G beta 5 complex closed state 8
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ...
Authors:Wang, S, Sass, M, Willardson, B.M, Shen, P.S.
Deposit date:2023-04-13
Release date:2023-10-25
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller.
Mol.Cell, 83, 2023
8UP2
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BU of 8up2 by Molmil
Murine Fab JAR 4 bound to meningococcal Factor H binding protein
Descriptor: ACETATE ION, Factor H binding protein, sequence variant ID 1, ...
Authors:Beernink, P.T, Beernink, B.P.
Deposit date:2023-10-20
Release date:2024-10-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of murine Fab JAR 4 bound to FHbp at 1.60-Angstroms resolution
To Be Published
1Z6O
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BU of 1z6o by Molmil
Crystal Structure of Trichoplusia ni secreted ferritin
Descriptor: CALCIUM ION, FE (III) ION, Ferritin heavy chain, ...
Authors:Hamburger, A.E, West Jr, A.P, Hamburger, Z.A, Hamburger, P, Bjorkman, P.J.
Deposit date:2005-03-22
Release date:2005-05-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Crystal structure of a secreted insect ferritin reveals a symmetrical arrangement of heavy and light chains.
J.Mol.Biol., 349, 2005
8SHL
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BU of 8shl by Molmil
CCT G beta 5 complex closed state 5
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ...
Authors:Wang, S, Sass, M, Willardson, B.M, Shen, P.S.
Deposit date:2023-04-14
Release date:2023-10-25
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller.
Mol.Cell, 83, 2023
5KKU
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BU of 5kku by Molmil
Crystal structure of an N-terminal dehydratase from difficidin assembly line
Descriptor: Polyketide synthase type I
Authors:Keatinge-Clay, A.T, Zeng, J.
Deposit date:2016-06-22
Release date:2016-12-21
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:A Dehydratase Provides Insights into Split Bimodules and Polypeptide Docking in trans-AT Polyketide Synthases
To Be Published
8SH9
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BU of 8sh9 by Molmil
CCT G beta 5 complex best PhLP1 class
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ...
Authors:Wang, S, Sass, M, Willardson, B.M, Shen, P.S.
Deposit date:2023-04-13
Release date:2023-10-25
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller.
Mol.Cell, 83, 2023
1ZE1
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BU of 1ze1 by Molmil
Conformational Change of Pseudouridine 55 Synthase upon Its Association with RNA Substrate
Descriptor: MAGNESIUM ION, tRNA pseudouridine synthase B
Authors:Phannachet, K, Huang, R.H.
Deposit date:2005-04-16
Release date:2005-04-26
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Conformational change of pseudouridine 55 synthase upon its association with RNA substrate
Nucleic Acids Res., 32, 2004
8SHF
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BU of 8shf by Molmil
CCT-G beta 5 complex closed state 7
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Guanine nucleotide-binding protein subunit beta-5, ...
Authors:Wang, S, Sass, M, Willardson, B.M, Shen, P.S.
Deposit date:2023-04-14
Release date:2023-11-01
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Visualizing the chaperone-mediated folding trajectory of the G protein beta 5 beta-propeller.
Mol.Cell, 83, 2023

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數據於2024-10-16公開中

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