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7Q3Q
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BU of 7q3q by Molmil
Crystal structure of SARS-CoV-2 RBD in complex with the neutralizing nanobody VHH-12
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ...
Authors:Fernandez, I, Pederzoli, R, Rey, F.A.
Deposit date:2021-10-28
Release date:2022-11-16
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:NANOBODIES AGAINST SARS-COV-2 NEUTRALIZE VARIANTS OF CONCERN AND EXPLORE CONFORMATIONAL DIFFERENCES ON THE SPIKE PROTEIN
To Be Published
7RXD
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BU of 7rxd by Molmil
CryoEM structure of RBD domain of COVID-19 in complex with Legobody
Descriptor: Fab_8D3_2 heavy chain, Fab_8D3_2 light chain, Maltodextrin-binding protein,Immunoglobulin G-binding protein A,Immunoglobulin G-binding protein G, ...
Authors:Wu, X.D, Rapoport, T.A.
Deposit date:2021-08-22
Release date:2021-10-06
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure determination of small proteins by nanobody-binding scaffolds (Legobodies).
Proc.Natl.Acad.Sci.USA, 118, 2021
7RTD
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BU of 7rtd by Molmil
SARS-CoV-2 Spike-derived peptide S269-277 (YLQPRTFLL) presented by HLA-A*02:01
Descriptor: Beta-2-microglobulin, HLA class I antigen, Spike protein S1
Authors:Szeto, C, Nguyen, A.T, Gras, S.
Deposit date:2021-08-13
Release date:2021-10-13
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Molecular Basis of a Dominant SARS-CoV-2 Spike-Derived Epitope Presented by HLA-A*02:01 Recognised by a Public TCR.
Cells, 10, 2021
7RTR
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BU of 7rtr by Molmil
YLQ-SG3 TCR in complex with SARS-CoV-2 Spike-derived peptide S269-277 (YLQPRTFLL) presented by HLA-A*02:01
Descriptor: Beta-2-microglobulin, HLA class I antigen, SODIUM ION, ...
Authors:Szeto, C, Gras, S.
Deposit date:2021-08-14
Release date:2021-10-13
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular Basis of a Dominant SARS-CoV-2 Spike-Derived Epitope Presented by HLA-A*02:01 Recognised by a Public TCR.
Cells, 10, 2021
7R15
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BU of 7r15 by Molmil
Alpha Variant SARS-CoV-2 Spike with 2 Erect RBDs
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Benton, D.J, Wrobel, A.G, Gamblin, S.J.
Deposit date:2022-02-02
Release date:2022-03-02
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Evolution of the SARS-CoV-2 spike protein in the human host.
Nat Commun, 13, 2022
7R10
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BU of 7r10 by Molmil
Dissociated S1 domain of Alpha Variant SARS-CoV-2 Spike bound to ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ...
Authors:Benton, D.J, Wrobel, A.G, Gamblin, S.J.
Deposit date:2022-02-02
Release date:2022-03-02
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Evolution of the SARS-CoV-2 spike protein in the human host.
Nat Commun, 13, 2022
7R1A
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BU of 7r1a by Molmil
Furin Cleaved Alpha Variant SARS-CoV-2 Spike in complex with 3 ACE2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:Benton, D.J, Wrobel, A.G, Gamblin, S.J.
Deposit date:2022-02-02
Release date:2022-03-02
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Evolution of the SARS-CoV-2 spike protein in the human host.
Nat Commun, 13, 2022
7R12
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BU of 7r12 by Molmil
Dissociated S1 domain of Mink Variant SARS-CoV-2 Spike bound to ACE2 (Non-Uniform Refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ...
Authors:Benton, D.J, Wrobel, A.G, Gamblin, S.J.
Deposit date:2022-02-02
Release date:2022-03-09
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Evolution of the SARS-CoV-2 spike protein in the human host.
Nat Commun, 13, 2022
7R11
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BU of 7r11 by Molmil
Dissociated S1 domain of Beta Variant SARS-CoV-2 Spike bound to ACE2 (Non-Uniform Refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ...
Authors:Benton, D.J, Wrobel, A.G, Gamblin, S.J.
Deposit date:2022-02-02
Release date:2022-03-09
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Evolution of the SARS-CoV-2 spike protein in the human host.
Nat Commun, 13, 2022
7R0Z
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BU of 7r0z by Molmil
Dissociated S1 domain of Alpha Variant SARS-CoV-2 Spike bound to ACE2 (Non-Uniform Refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ...
Authors:Benton, D.J, Wrobel, A.G, Gamblin, S.J.
Deposit date:2022-02-02
Release date:2022-03-09
Last modified:2022-03-16
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Evolution of the SARS-CoV-2 spike protein in the human host.
Nat Commun, 13, 2022
7RZS
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BU of 7rzs by Molmil
Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with L938F mutation
Descriptor: SARS-CoV-2 HR1 L938F linked to a scaffold,Spike protein S2', Spike protein S2'
Authors:Yang, K, Brunger, A.T.
Deposit date:2021-08-27
Release date:2022-04-06
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.52 Å)
Cite:Structural conservation among variants of the SARS-CoV-2 spike postfusion bundle.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RZR
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BU of 7rzr by Molmil
Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with D936Y mutation
Descriptor: SARS-CoV-2 HR1 D936Y linked to a scaffold,Spike protein S2', Spike protein S2'
Authors:Yang, K, Brunger, A.T.
Deposit date:2021-08-27
Release date:2022-04-06
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.27 Å)
Cite:Structural conservation among variants of the SARS-CoV-2 spike postfusion bundle.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RZT
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BU of 7rzt by Molmil
Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with S940F mutation
Descriptor: SARS-CoV-2 HR1 S940F linked to a scaffold,Spike protein S2', Spike protein S2'
Authors:Yang, K, Brunger, A.T.
Deposit date:2021-08-27
Release date:2022-04-06
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.35 Å)
Cite:Structural conservation among variants of the SARS-CoV-2 spike postfusion bundle.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RZU
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BU of 7rzu by Molmil
Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with A942S mutation
Descriptor: SARS-CoV-2 HR1 A942S linked to a scaffold,Spike protein S2', Spike protein S2'
Authors:Yang, K, Brunger, A.T.
Deposit date:2021-08-27
Release date:2022-04-06
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Structural conservation among variants of the SARS-CoV-2 spike postfusion bundle.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RZQ
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BU of 7rzq by Molmil
Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex
Descriptor: SARS-CoV-2 HR1 linked to a scaffold,Spike protein S2', Spike protein S2'
Authors:Yang, K, Brunger, A.T.
Deposit date:2021-08-27
Release date:2022-04-06
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.09 Å)
Cite:Structural conservation among variants of the SARS-CoV-2 spike postfusion bundle.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RZV
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BU of 7rzv by Molmil
Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with V1176F mutation
Descriptor: SARS-CoV-2 HR1 linked to a scaffold,Spike protein S2', Spike protein S2'
Authors:Yang, K, Brunger, A.T.
Deposit date:2021-08-27
Release date:2022-04-06
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.11 Å)
Cite:Structural conservation among variants of the SARS-CoV-2 spike postfusion bundle.
Proc.Natl.Acad.Sci.USA, 119, 2022
8CMI
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BU of 8cmi by Molmil
Human Leukocyte Antigen class II allotype DR1 presenting SARS-CoV-2 Omicron (BA.1) Spike peptide S761-775
Descriptor: 1,2-ETHANEDIOL, HLA class II histocompatibility antigen, DR alpha chain, ...
Authors:MacLachlan, B.J, Mason, G.H, Sourfield, D.O, Godkin, A.J, Rizkallah, P.J.
Deposit date:2023-02-19
Release date:2023-07-26
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4 + T cell immunity.
Cell Rep, 42, 2023
8CMD
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BU of 8cmd by Molmil
Human Leukocyte Antigen class II allotype DR1 presenting SARS-CoV-2 Spike peptide S761-775
Descriptor: 1,2-ETHANEDIOL, HLA class II histocompatibility antigen, DR alpha chain, ...
Authors:MacLachlan, B.J, Mason, G.H, Sourfield, D.O, Godkin, A.J, Rizkallah, P.J.
Deposit date:2023-02-19
Release date:2023-07-26
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4 + T cell immunity.
Cell Rep, 42, 2023
8CMH
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BU of 8cmh by Molmil
Human Leukocyte Antigen class II allotype DR1 presenting SARS-CoV-2 Omicron (BA.1) Spike peptide S486-505
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-ETHANETHIOL, HLA class II histocompatibility antigen, ...
Authors:MacLachlan, B.J, Mason, G.H, Sourfield, D.O, Godkin, A.J, Rizkallah, P.J.
Deposit date:2023-02-19
Release date:2023-07-26
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4 + T cell immunity.
Cell Rep, 42, 2023
8CMC
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BU of 8cmc by Molmil
Human Leukocyte Antigen class II allotype DR1 presenting SARS-CoV-2 Spike peptide S511-530
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, HLA class II histocompatibility antigen, ...
Authors:MacLachlan, B.J, Mason, G.H, Sourfield, D.O, Godkin, A.J, Rizkallah, P.J.
Deposit date:2023-02-19
Release date:2023-07-26
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4 + T cell immunity.
Cell Rep, 42, 2023
8CMB
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BU of 8cmb by Molmil
Human Leukocyte Antigen class II allotype DR1 presenting SARS-CoV-2 Spike peptide S486-505
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-ETHANETHIOL, HLA class II histocompatibility antigen, ...
Authors:MacLachlan, B.J, Mason, G.H, Godkin, A.J, Rizkallah, P.J.
Deposit date:2023-02-19
Release date:2023-07-26
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4 + T cell immunity.
Cell Rep, 42, 2023
8C5R
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BU of 8c5r by Molmil
Omicron B.1.1.529 2 RBD up conformation
Descriptor: Spike glycoprotein
Authors:Raghavan, S.S.R, Walker, M.R, Salanti, A, Barfod, L.K, Wang, K.T.
Deposit date:2023-01-10
Release date:2024-01-24
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Omicron B.1.1.529 2 RBD up conformation
To Be Published
8CZI
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BU of 8czi by Molmil
Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with extended HR2
Descriptor: Scaffolded Spike protein S2' HR1, Spike protein S2' HR2
Authors:Yang, K, Brunger, A.T.
Deposit date:2022-05-24
Release date:2022-09-07
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.22 Å)
Cite:Nanomolar inhibition of SARS-CoV-2 infection by an unmodified peptide targeting the prehairpin intermediate of the spike protein.
Proc.Natl.Acad.Sci.USA, 119, 2022
8DAO
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BU of 8dao by Molmil
Crystal structure of SARS-CoV-2 spike stem fusion peptide in complex with neutralizing antibody COV44-79
Descriptor: COV44-79 heavy chain constant domain, COV44-79 heavy chain variable domain, COV44-79 light chain constant domain, ...
Authors:Lin, T.H, Lee, C.C.D, Yuan, M, Wilson, I.A.
Deposit date:2022-06-13
Release date:2022-07-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Broadly neutralizing antibodies target the coronavirus fusion peptide.
Science, 377, 2022
8DF5
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BU of 8df5 by Molmil
SARS-CoV-2 Beta RBD in complex with human ACE2 and S304 Fab and S309 Fab
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:McCallum, M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Snell, G, Veesler, D.
Deposit date:2022-06-21
Release date:2022-08-03
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Shifting mutational constraints in the SARS-CoV-2 receptor-binding domain during viral evolution.
Science, 377, 2022

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數據於2024-11-06公開中

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